Evidence map›Paper›PMID 34867351›Full record

ArticleFrontiers in pharmacology2021

Pathogenic in-Frame Variants in

Jennifer C Wong, Kameryn M Butler, Lindsey Shapiro, Jacquelyn T Thelin, Kari A Mattison, Kathryn B Garber, Paula C Goldenberg, Shobana Kubendran, G Bradley Schaefer, Andrew Escayg

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jennifer C WongDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Kameryn M ButlerDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Lindsey ShapiroDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Jacquelyn T ThelinDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Kari A MattisonDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Kathryn B GarberDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Paula C GoldenbergDepartment of Pediatrics and Medical Genetics, Harvard Medical School, Boston, MA, United States.
Shobana KubendranDepartment of Pediatrics, Kansas University School of Medicine-Wichita, Wichita, KS, United States.
G Bradley SchaeferUniversity of Arkansas for Medical Sciences, Little Rock, AR, United States.
Andrew EscaygDepartment of Human Genetics, Emory University, Atlanta, GA, United States.
Emory University · USHarvard University · USUniversity of Arkansas for Medical Sciences · USWichita State University · US

Funding

Training In Systems And Integrative Biology NeuroscienceT32NS096050 · NINDS · EMORY UNIVERSITY · PI Yoland Smith · 2016 to 2026
$3.9M
Exploring the range of seizure and behavioral phenotypes due to SCN8A mutationsR03NS114791 · NINDS · EMORY UNIVERSITY · PI ESCAYG, ANDREW P · 2020 to 2020
$151k
NINDS NIH HHS R03 NS114791NINDS NIH HHS T32 NS096050
6 · The paper itself

Abstract

Numerous

Indexed as

epilepsymousemutationSCN8Aseizuresodium channel

Identifiers

PMID34867351
PMCPMC8635767
OpenAlexW4200614528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.