Evidence map›Paper›PMID 34867278›Full record

ArticleFrontiers in aging neuroscience2021

The Association Between Lysosomal Storage Disorder Genes and Parkinson's Disease: A Large Cohort Study in Chinese Mainland Population.

Yu-Wen Zhao, Hong-Xu Pan, Zhenhua Liu, Yige Wang, Qian Zeng, Zheng-Huan Fang, Teng-Fei Luo, Kun Xu, Zheng Wang, Xun Zhou and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Rare-Variant Burden across Lysosomal Genes Implicates Sialylation and Ganglioside Metabolism in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  2. ThemedRxiv : the preprint server for health sciences · 2026
    Article
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  13. Association Study ofFrontiers in neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Yu-Wen ZhaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Hong-Xu PanDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Zhenhua LiuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Yige WangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Qian ZengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Zheng-Huan FangCentre for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Teng-Fei LuoCentre for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Kun XuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Zheng WangNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Xun ZhouDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.
Runcheng HeDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Bin LiNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Guihu ZhaoNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Qian XuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Qi-Ying SunDepartment of Geriatrics, Xiangya Hospital, Central South University, Changsha, China.
Xin-Xiang YanDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Jie-Qiong TanCentre for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Jin-Chen LiNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Ji-Feng GuoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Bei-Sha TangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Xiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GBAlysosomal storage disorderslysosomeParkinson’s diseaserare putative damaging variants

Identifiers

PMID34867278
PMCPMC8634711
OpenAlexW3213913506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.