ArticleFrontiers in computational neuroscience2021
Analysis of the Neuron Dynamics in Thalamic Reticular Nucleus by a Reduced Model.
Article in Frontiers in computational neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to spindle dynamics.iScience · 2025Article
- Dynamics of antiphase bursting modulated by the inhibitory synaptic and hyperpolarization-activated cation currents.Frontiers in computational neuroscience · 2024Article
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3 authors.
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Abstract
Strategically located between the thalamus and the cortex, the inhibitory thalamic reticular nucleus (TRN) is a hub to regulate selective attention during wakefulness and control the thalamic and cortical oscillations during sleep. A salient feature of TRN neurons contributing to these functions is their characteristic firing patterns, ranging in a continuum from tonic spiking to bursting spiking. However, the dynamical mechanism under these firing behaviors is not well understood. In this study, by applying a reduction method to a full conductance-based neuron model, we construct a reduced three-variable model to investigate the dynamics of TRN neurons. We show that the reduced model can effectively reproduce the spiking patterns of TRN neurons as observed
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