Evidence map›Paper›PMID 34867187›Full record

ArticleFrontiers in molecular neuroscience2021

Rab11a Regulates the Development of Cilia and Establishment of Planar Cell Polarity in Mammalian Vestibular Hair Cells.

Bin-Jun Chen, Xiao-Qing Qian, Xiao-Yu Yang, Tao Jiang, Yan-Mei Wang, Ji-Han Lyu, Fang-Lu Chi, Ping Chen, Dong-Dong Ren

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. AFrontiers in genetics · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Bin-Jun ChenDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Xiao-Qing QianDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Xiao-Yu YangDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Tao JiangDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Yan-Mei WangDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Ji-Han LyuDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Fang-Lu ChiDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Ping ChenDepartment of Cell Biology, Emory University, Atlanta, GA, United States.
Dong-Dong RenDepartment of Otorhinolaryngology, ENT Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
Eye & ENT Hospital of Fudan University · CNFudan University · CNShanghai Medical Information Center · CNEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vestibular organs have unique planar cell polarity (Figure 1A), and their normal development and function are dependent on the regular polarity of cilia (Figure 1B) requires. Rab11a is a small G protein that participates in the transportation of intracellular and extracellular materials required for polarity formation; however, our understanding of the mechanisms of the actions of Rab11a in vestibular organs is limited. Here, we showed that the general shape of the utricle was abnormal in

Indexed as

ciliadevelopmentplanar cell polarityRab11avestibular

Identifiers

PMID34867187
PMCPMC8640494
OpenAlexW4206469471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.