Evidence map›Paper›PMID 34867090›Full record

ArticlePathology oncology research : POR2021

Profiling Activins and Follistatin in Colorectal Cancer According to Clinical Stage, Tumour Sidedness and Smad4 Status.

Bassem Refaat, Jamal Zekri, Akhmed Aslam, Jawwad Ahmad, Mohammed A Baghdadi, Abdelrazak Meliti, Shakir Idris, Sufian Sultan, Hosam Alardati, Haitham Akram Saimeh and 5 more

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Bassem RefaatLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Jamal ZekriOncology Department, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Akhmed AslamLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Jawwad AhmadLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Mohammed A BaghdadiResearch Centre, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Abdelrazak MelitiPathology Department, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Shakir IdrisLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Sufian SultanDepartment of Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Hosam AlardatiPathology Department, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Haitham Akram SaimehDepartment of Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Aiman AlsaeghLaboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Mai AlhadramiPathology Department, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Tahira HamidHistopathology Department, King Abdullah Medical City, Makkah, Saudi Arabia.
Mohammed E NaeemHistopathology Department, King Abdullah Medical City, Makkah, Saudi Arabia.
Shereef Ahmed ElsamanyMedical Oncology Department, Oncology Centre, King Abdullah Medical City, Makkah, Saudi Arabia.
Umm al-Qura University · SAKing Faisal Specialist Hospital & Research Centre · SAKing Abdullah Medical City · SAAlfaisal University · SAMansoura University · EGUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the roles of activins and follistatin in colorectal cancers. Paired malignant and normal colonic tissues were collected from archived paraffin-embedded (

Indexed as

ActivinsApoptosisBiomarkers, TumorCell CycleCell Cycle ProteinsCell Line, TumorColorectal NeoplasmsDisease ProgressionFemaleFollistatinHumansInhibin-beta SubunitsMaleRNA, MessengerSmad4 ProteinActivinsBiomarkers, TumorCell Cycle ProteinsFollistatinFST protein, humanInhibin-beta SubunitsRNA, MessengerSmad4 ProteinSMAD4 protein, humanactivin-Aactivin-ABactivin-Bapoptosiscell cyclefollistatin

Identifiers

PMID34867090
PMCPMC8634429
OpenAlexW3212883988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.