Evidence map›Paper›PMID 34866935›Full record

ArticleInternational journal of general medicine2021

Impact of Comorbidities on the Prognosis of Pediatric Postural Tachycardia Syndrome.

Yaru Wang, Junbao Du, Xueying Li, Ping Liu, Yuli Wang, Ying Liao, Hongfang Jin

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yaru WangDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Junbao DuDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Xueying LiDepartment of Medical Statistics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Ping LiuDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Yuli WangDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Ying LiaoDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Hongfang JinDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, People's Republic of China.
Peking University First Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the influence of comorbidities on the prognosis of pediatric postural tachycardia syndrome (POTS).

methodsIn this retrospective cohort study, 275 children with POTS admitted to the Department of Pediatrics at Peking University First Hospital were recruited from 2016 to 2019 and followed up. The participants were divided into simple POTS (S-POTS, n=156 cases) and POTS with comorbidities (Co-POTS, n=119 cases) groups according to whether they were complicated with comorbidities. A Cox regression analysis was used to identify the prognostic risk factors for children with POTS, while Kaplan-Meier curves were applied to compare the cumulative symptom remission rate (CSRR) between the two groups. The rehospitalization of the children between the two groups was also compared to explore the influence of comorbidities.

resultsTwenty-one participants (7.6%) were lost during a median follow-up of 24 months. The Cox regression model showed that comorbidities and body mass index (BMI) were associated with the CSRR of the children with POTS. The CSRR of pediatric POTS alone was 1.748 times higher than that of patients with comorbidities, and the CSRR was decreased by 5.1% for each 1 kg/m

conclusionComplicating with comorbidities, pediatric patients with POTS had lower CSRR and more rehospitalizations than those without comorbidities. More attention should be given to comorbidities when managing pediatric POTS.

Indexed as

allergic disorderschildrencomorbiditypostural tachycardia syndromeprognosis

Identifiers

PMID34866935
PMCPMC8636694
OpenAlexW3217071611

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.