Evidence map›Paper›PMID 34866796›Full record

ArticleSensors and actuators. B, Chemical2022

COVID-19 diagnosis by SARS-CoV-2 Spike protein detection in saliva using an ultrasensitive magneto-assay based on disposable electrochemical sensor.

Evair D Nascimento, Wilson T Fonseca, Tássia R de Oliveira, Camila R S T B de Correia, Vitor M Faça, Beatriz P de Morais, Virginia C Silvestrini, Henrique Pott-Junior, Felipe R Teixeira, Ronaldo C Faria

Open access · greenAbstract read
In one paragraph

Article in Sensors and actuators. B, Chemical, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 80 citations in OpenAlex.

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  17. NMR-Metabolomics in COVID-19 Research.Advances in experimental medicine and biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Evair D NascimentoDepartment of Chemistry, Federal University of São Carlos-UFSCar, Rod. Washington Luís km 235, São Carlos, SP, 13565-905, Brazil.
Wilson T FonsecaDepartment of Chemistry, Federal University of São Carlos-UFSCar, Rod. Washington Luís km 235, São Carlos, SP, 13565-905, Brazil.
Tássia R de OliveiraDepartment of Chemistry, Federal University of São Carlos-UFSCar, Rod. Washington Luís km 235, São Carlos, SP, 13565-905, Brazil.
Camila R S T B de CorreiaDepartment of Genetics and Evolution, Federal University of Sao Carlos-UFSCar, São Carlos, SP, 13565-905, Brazil.
Vitor M FaçaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo-USP, Brazil.
Beatriz P de MoraisDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo-USP, Brazil.
Virginia C SilvestriniDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo-USP, Brazil.
Henrique Pott-JuniorDepartment of Medicine, Federal University of São Carlos-UFSCar, São Carlos, SP, 13565-905, Brazil.
Felipe R TeixeiraDepartment of Genetics and Evolution, Federal University of Sao Carlos-UFSCar, São Carlos, SP, 13565-905, Brazil.
Ronaldo C FariaDepartment of Chemistry, Federal University of São Carlos-UFSCar, Rod. Washington Luís km 235, São Carlos, SP, 13565-905, Brazil.
Universidade Federal de São Carlos · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of the COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome of Coronavirus 2 (SARS-CoV-2), has fueled the search for diagnostic tests aiming at the control and reduction of the viral transmission. The main technique used for diagnosing the Coronavirus disease (COVID-19) is the reverse transcription-polymerase chain reaction (RT-PCR) technique. However, considering the high number of cases and the underlying limitations of the RT-PCR technique, especially with regard to accessibility and cost of the test, one does not need to overemphasize the need to develop new and less expensive testing techniques that can aid the early diagnosis of the disease. With that in mind, we developed an ultrasensitive magneto-assay using magnetic beads and gold nanoparticles conjugated to human angiotensin-converting enzyme 2 (ACE2) peptide (Gln

Indexed as

COVID-19 DiagnosisElectrochemical DeviceSalivaSARS-CoV-2Spike Protein

Identifiers

PMID34866796
PMCPMC8626148
OpenAlexW3216558806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.