Evidence map›Paper›PMID 34866775›Full record

ArticleIndustrial & engineering chemistry research2021

Recovery of Magnetic Catalysts: Advanced Design for Process Intensification.

Cristina González-Fernández, Jenifer Gómez-Pastora, Eugenio Bringas, Maciej Zborowski, Jeffrey J Chalmers, Inmaculada Ortiz

Abstract read
In one paragraph

Article in Industrial & engineering chemistry research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Modular Attachment of Nanoparticles on Microparticle Supports via Multifunctional Polymers.Chemistry of materials : a publication of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina González-FernándezDepartment of Chemical and Biomolecular Engineering, ETSIIT, University of Cantabria, Avda. Los Castros s/n, 39005 Santander, Spain.ORCID https://orcid.org/0000-0002-1571-057X
Jenifer Gómez-PastoraWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 W. Woodruff Avenue, Columbus, Ohio 43210, United States.ORCID https://orcid.org/0000-0002-5157-4130
Eugenio BringasDepartment of Chemical and Biomolecular Engineering, ETSIIT, University of Cantabria, Avda. Los Castros s/n, 39005 Santander, Spain.
Maciej ZborowskiDepartment of Biomedical Engineering Cleveland Clinic 9500 Euclid Avenue, Cleveland, Ohio 44195, United States.
Jeffrey J ChalmersWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 W. Woodruff Avenue, Columbus, Ohio 43210, United States.ORCID https://orcid.org/0000-0003-1723-9774
Inmaculada OrtizDepartment of Chemical and Biomolecular Engineering, ETSIIT, University of Cantabria, Avda. Los Castros s/n, 39005 Santander, Spain.ORCID https://orcid.org/0000-0002-3257-4821

Funding

Magnetophoretic Cell Sorting and AnalysisR01CA062349 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI ZBOROWSKI, MACIEJ · 1994 to 2015
$5.5M
Fractionation of Aged RBCs Based on Hemoglobin ContentR01HL131720 · NHLBI · OHIO STATE UNIVERSITY · PI CHALMERS, JEFFREY JOHN, PALMER, ANDRE FRANCIS · 2017 to 2020
$2.7M
NCI NIH HHS R01 CA062349NHLBI NIH HHS R01 HL131720
6 · The paper itself

Abstract

The design of microdevices in which components with magnetic character must be separated and recovered from reactive media benefits from the advantages of microfluidics and meets the criteria for process intensification; however, there are open questions, such as the design of the most appropriate magnet arrangement, that need further research in order to increase the magnetic gradient exerted on the particles. Herein, we focus on the continuous recovery of magnetic microparticles, that can be used as support to facilitate the recovery of biocatalysts (magnetic microcatalysts, MMCs) from biological fluids. We analyze and compare the performance of two typical magnetophoretic microdevices for addressing bead recovery: (i) annular channels with a quadrupole orientation of the permanent magnets (quadrupole magnetic sorter, QMS) and (ii) the standard design, which consists of rectangular channels with a single permanent magnet to generate the magnetic field. To this end, an experimentally validated computational fluid dynamics (CFD) numerical model has been employed. Our results reveal that for devices with the same width and length, the micro-QMS, in comparison to a rectangular channel, could accomplish the complete particle retrieval while (i) processing more than 4 times higher fluid velocities, treating more than 360 times higher flow rates or (ii) working with smaller particles, thus reducing by 55% the particle mass. Additionally, the parallel performance of ≈300 micro-QMSs fulfills the processing of flow rates as high as 200 L·h

Identifiers

PMID34866775
PMCPMC8630691

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.