ArticleMicrochemical journal : devoted to the application of microtechniques in all branches of science2022
Fluorescence immunoassay rapid detection of 2019-nCoV antibody based on the fluorescence resonance energy transfer between graphene quantum dots and Ag@Au nanoparticle.
Article in Microchemical journal : devoted to the application of microtechniques in all branches of science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 21 citations in OpenAlex.
- Identification of geographical origins of Ophiocordyceps sinensis (Berk.) via machine learning-assisted surface-enhanced Raman spectroscopy.Analytical and bioanalytical chemistry · 2026Article
- Advances in rapid detection technologies for zoonotic diseases: a one health-oriented review.Frontiers in cellular and infection microbiology · 2026Review
- Recent applications of near infrared to pharmaceutical process monitoring and quality control.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Review
- Fast and Sensitive Detection of Anti-SARS-CoV-2 IgG Using SiOBiomolecules · 2024Article
- Graphene-Oxide Peptide-Containing Materials for Biomedical Applications.International journal of molecular sciences · 2024Review
- Revealing the high efficiency of fluorescence quenching of rhodamine B by triangular silver nanodisks due to the inner filter effect mechanism.RSC advances · 2024Article
- Detection of SARS-CoV-2 S protein based on FRET between carbon quantum dots and gold nanoparticles.Heliyon · 2023Article
- Efficient interfacial self-assembled MXene/Ag NPs film nanocarriers for SERS-traceable drug delivery.Analytical and bioanalytical chemistry · 2023Article
- Prediction of microseismic events in rock burst mines based on MEA-BP neural network.Scientific reports · 2023Article
- A FRET Fluorescent Sensor for Ratiometric and Visual Detection of Sulfide Based on Carbon Dots and Silver Nanoclusters.Journal of fluorescence · 2022Article
- Pulsed-sonochemiluminescence combined with molecularly imprinted polymerized high internal phase emulsion adsorbent for determination of bentazone.Mikrochimica acta · 2022Article
- Recent Developments in the Field of Optical Immunosensors Focusing on a Label-Free, White Light Reflectance Spectroscopy-Based Immunosensing Platform.Sensors (Basel, Switzerland) · 2022Review
- A label-free photoelectrochemical sensor of S, N co-doped graphene quantum dot (S, N-GQD)-modified electrode for ultrasensitive detection of bisphenol A.Mikrochimica acta · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has dramatically changed the world, is a highly contagious virus. The timely and accurate diagnosis of SARS-CoV-2 infections is vital for disease control and prevention. Here in this work, a fluorescence immunoassay was developed to detect 2019 Novel Coronavirus antibodies (2019-nCoV mAb). Fluorescent graphene quantum dots (GQDs) and Ag@Au nanoparticles (Ag@AuNPs) were successfully synthesized and characterized. Fluorescence resonance energy transfer (FRET) enables effective quenching of GQDs fluorescence by Ag@AuNPs. With the presence of 2019-nCoV mAb, a steric hindrance was observed between the Ag@AuNPs-NCP (2019-nCoV antigen) complex and GQDs, which reduced the FRET efficiency and restored the fluorescence of GQDs. The fluorescence enhancement efficiency has a satisfactory linear relationship with the logarithm of the 2019-nCoV mAb in a concentration range of 0.1 pg mL
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