Evidence map›Paper›PMID 34866370›Full record

ArticleJournal of clinical research in pediatric endocrinology2023

Non-hormonal Clitoromegaly due to Clitoral Priapism Caused by Appendicitis/Appendectomy

Büşra Gürpınar Tosun, Ahsen Karagözlü Akgül, Eda Almus, Sadık Abidoğlu, Serap Turan, Abdullah Bereket, Tülay Güran

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Büşra Gürpınar TosunMarmara University Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, İstanbul, TurkeyORCID 0000-0002-7588-9807
Ahsen Karagözlü AkgülMarmara University Faculty of Medicine, Department of Pediatric Urology, İstanbul, TurkeyORCID 0000-0003-3250-605X
Eda AlmusMarmara University Faculty of Medicine, Department of Pediatric Radiology, İstanbul, TurkeyORCID 0000-0002-9452-0474
Sadık AbidoğluMarmara University Faculty of Medicine, Department of Pediatric Urology, İstanbul, TurkeyORCID 0000-0002-8654-8856
Serap TuranMarmara University Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, İstanbul, TurkeyORCID 0000-0002-5172-5402
Abdullah BereketMarmara University Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, İstanbul, TurkeyORCID 0000-0002-6584-9043
Tülay GüranMarmara University Faculty of Medicine, Department of Pediatric Endocrinology and Diabetes, İstanbul, TurkeyORCID 0000-0003-2658-6866
Marmara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clitoromegaly usually develops due to hyperandrogenism. There are a few cases of clitoromegaly described without clinical and biochemical hyperandrogenism. Clitoromegaly due to clitoral priapism and clitoral priapism after appendectomy have not been reported previously. A 7-year-old girl was referred for enlargement of the clitoris. She reported having a mild, pulsating clitoral pain starting three days after an appendectomy operation. Subsequently, painful swelling and an increase in the size of the clitoris was observed. Her growth and physical examination were otherwise normal. Causes of the clitoromegaly due to androgen excess were excluded after a comprehensive work-up. Color Doppler ultrasound revealed a high peak systolic velocity and resistance in the cavernosal artery, consistent with clitoral priapism. The clitoromegaly and associated symptoms improved significantly with oral pseudoephedrine and intracavernosal aspiration. This unique case illustrates that clitoral priapism is a rare, non-hormonal cause of clitoromegaly and may occur after appendectomy. Pseudoephedrine treatment is helpful in alleviating the symptoms.

Indexed as

AppendicitisHyperandrogenismPriapismAppendectomyChildClitorisFemaleHumansMalePseudoephedrinePseudoephedrineacute appendicitisclitoral priapismclitorismNon-hormonal clitoromegalypelvic inflammationpseudoephedrine

Identifiers

PMID34866370
PMCPMC10448556
OpenAlexW4200520355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.