Evidence map›Paper›PMID 34866350›Full record

ReviewThoracic cancer2022

Primary EWS/PNET of the lung with TP53 germline and SKT11 somatic mutation: A case report and review of the literature.

Shuangping Zhang, Yun Chen, Shiping Guo, Ke-Neng Chen

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Thoracic cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A rare radiotherapy-sensitive primitive neuroectodermal tumor withThe Journal of international medical research · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shuangping ZhangDepartment of Thoracic Surgery, Shanxi Cancer Hospital, Taiyuan, China.ORCID 0000-0002-8321-4690
Yun ChenDepartment of Operating Room Nursing, Shanxi Cancer Hospital, Taiyuan, China.
Shiping GuoDepartment of Thoracic Surgery, Shanxi Cancer Hospital, Taiyuan, China.
Ke-Neng ChenThe First Department of Thoracic Surgery, Peking University Cancer Hospital & Institute, Beijing, China.ORCID 0000-0002-0757-7094
Shanxi Provincial Cancer Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary pulmonary EWS/PNET is extremely rare. This report describes a 20 year-old man with primary pulmonary EWS/PNET with TP53 germline and SKT11 somatic mutation. After four neoadjuvant chemotherapy cycles (VAC with alternating IE) combined with anlotinib, a left pneumonectomy was performed. Maintenance anlotinib monotherapy was then continued with no sign of recurrence to date. It is suggested that before the treatment and prognosis of children or young adults with primary EWS/PNET of the lung that consideration should be given to genetic testing.

Indexed as

Combined Modality TherapyExome SequencingGerm-Line MutationHumansLymphatic MetastasisMaleNeuroectodermal Tumors, PrimitivePneumonectomyProteinsRNA-Binding Protein EWSSarcoma, EwingTumor Suppressor Protein p53Young AdultKIAA1217 protein, humanProteinsRNA-Binding Protein EWSTP53 protein, humanTumor Suppressor Protein p53Ewing's sarcomapulmonaryTP53

Identifiers

PMID34866350
PMCPMC8720619
OpenAlexW4200509133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.