ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022
Impact of percutaneous coronary intervention of chronic total occlusions on absolute perfusion in remote myocardium.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Distal Vessel Diameter and Antegrade Crossing Success in Chronic Total Occlusion Percutaneous Coronary Intervention.CJC open · 2026Article
- Selecting the right patient for CTO-PCI: is ischaemia still the key?European heart journal. Imaging methods and practice · 2026Article
- Impact of myocardial perfusion abnormalities on clinical outcomes in patients treated with percutaneous coronary intervention for chronic total occlusions.European heart journal. Imaging methods and practice · 2026Article
- Role of Circulating Microparticles in Impairing Endothelial Function and Activating Oxidative Stress Is Related to No-Reflow in STEMI.Cardiovascular therapeutics · 2026Article
- Myocardial perfusion imaging in advanced coronary artery disease.European journal of clinical investigation · 2025Review
- Short-term changes in myocardial perfusion of the predominant donor vessel after percutaneous coronary intervention for chronic total occlusion.Quantitative imaging in medicine and surgery · 2025Article
- Prognostic value of global coronary flow reserve before and after elective percutaneous coronary intervention in patients with chronic coronary syndrome.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- Changes in absolute flow, myocardial resistance and FFR after chronic total occlusion percutaneous coronary intervention.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2023Observational
- Patient Selection and Clinical Indication for Chronic Total Occlusion Revascularization-A Workflow Focusing on Non-Invasive Cardiac Imaging.Life (Basel, Switzerland) · 2022Review
- The myocardial perfusion paradigm: a missing link between patient selection and appropriateness of treatment.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRevascularisation of a chronic total coronary occlusion (CTO) impacts the coronary physiology of the remote myocardial territory.
aimsThis study aimed to evaluate the intrinsic effect of CTO percutaneous coronary intervention (PCI) on changes in absolute perfusion in remote myocardium.
methodsA total of 164 patients who underwent serial [
resultsPerfusion indices in CTO and remote myocardium showed a positive correlation before (resting MBF: r=0.84, hMBF: r=0.75, and CFR: r=0.77, p<0.01 for all) and after (resting MBF: r=0.87, hMBF: r=0.87, and CFR: r=0.81, p<0.01 for all) CTO PCI. Absolute increases in hMBF and CFR were observed in remote myocardium following CTO revascularisation (from 2.29±0.67 to 2.48±0.75 mL·min
conclusionsCTO revascularisation resulted in an increase in remote myocardial perfusion. Furthermore, the quantitative improvement in hMBF and CFR in the CTO territory was independently associated with the absolute perfusion increase in remote myocardial regions. As such, CTO PCI may have a favourable physiologic impact beyond the intended treated myocardium.
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