Evidence map›Paper›PMID 34865622›Full record

ArticleBiomedical engineering online2021

Pulmonary lesion subtypes recognition of COVID-19 from radiomics data with three-dimensional texture characterization in computed tomography images.

Wei Li, Yangyong Cao, Kun Yu, Yibo Cai, Feng Huang, Minglei Yang, Weidong Xie

Abstract read
In one paragraph

Article in Biomedical engineering online, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wei LiKey Laboratory of Intelligent Computing in Medical Image (MIIC), Northeastern University, Ministry of Education, Shenyang, China.
Yangyong CaoSchool of Computer Science and Engineering, Northeastern University, Shenyang, China. 1971582@stu.neu.edu.cn.
Kun YuBiomedical and Information Engineering School, Northeastern University, Shenyang, China.
Yibo CaiSchool of Computer Science and Engineering, Northeastern University, Shenyang, China.
Feng HuangNeusoft Medical System Co., Ltd., Shenyang, Liaoning, China.
Minglei YangNeusoft Medical System Co., Ltd., Shenyang, Liaoning, China.
Weidong XieSchool of Computer Science and Engineering, Northeastern University, Shenyang, China. 1910638@stu.neu.edu.cn.ORCID http://orcid.org/0000-0003-1930-4509

Funding

Fundamental Research Funds for Central Universities of the Central South University N2016006National Natural Science Foundation of China No.U1708261Shenyang Medical Imaging Processing Engineering Technology Research Center 17-134-8-00
6 · The paper itself

Abstract

backgroundThe COVID-19 disease is putting unprecedented pressure on the global healthcare system. The CT (computed tomography) examination as a auxiliary confirmed diagnostic method can help clinicians quickly detect lesions locations of COVID-19 once screening by PCR test. Furthermore, the lesion subtypes classification plays a critical role in the consequent treatment decision. Identifying the subtypes of lesions accurately can help doctors discover changes in lesions in time and better assess the severity of COVID-19.

methodThe most four typical lesion subtypes of COVID-19 are discussed in this paper, which are GGO (ground-glass opacity), cord, solid and subsolid. A computer-aided diagnosis approach of lesion subtype is proposed in this paper. The radiomics data of lesions are segmented from COVID-19 patients CT images with diagnosis and lesions annotations by radiologists. Then the three-dimensional texture descriptors are applied on the volume data of lesions as well as shape and first-order features. The massive feature data are selected by HAFS (hybrid adaptive feature selection) algorithm and a classification model is trained at the same time. The classifier is used to predict lesion subtypes as side decision information for radiologists.

resultsThere are 3734 lesions extracted from the dataset with 319 patients collection and then 189 radiomics features are obtained finally. The random forest classifier is trained with data augmentation that the number of different subtypes of lesions is imbalanced in initial dataset. The experimental results show that the accuracy of the four subtypes of lesions is (93.06%, 96.84%, 99.58%, and 94.30%), the recall is (95.52%, 91.58%, 95.80% and 80.75%) and the f-score is (93.84%, 92.37%, 95.47%, and 84.42%).

conclusionThe three-dimensional radiomics features used in this paper can better express the high-level information of COVID-19 lesions in CT slices. HAFS method aggregates the results of multiple feature selection algorithms intersects with traditional methods to filter out redundant features more accurately. After selection, the subtype of COVID-19 lesion can be judged by inputting the features into the RF (random forest) model, which can help clinicians more accurately identify the subtypes of COVID-19 lesions and provide help for further research.

Indexed as

COVID-19AlgorithmsHumansLungSARS-CoV-2Tomography, X-Ray Computed3D texture featureCOVID-19Hybrid adaptive feature selectionLesion subtypesRadiomicsRandom forest

Identifiers

PMID34865622
PMCPMC8645296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.