ArticleThe Korean journal of internal medicine2022
The presence of simple renal cysts is associated with an increased risk of albuminuria in young adults.
Article in The Korean journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Engineered human induced pluripotent stem cell models reveal altered podocytogenesis in congenital heart disease-associated SMAD2 mutations.Nature biomedical engineering · 2026Article
- Associations between metabolic indices and the prevalence of simple renal cysts among hospitalized patients with hypertension in Xinjiang, China: a large-scale cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- GGPS1 Promoter Variant (rs3806394) Is Associated With Larger Simple Renal Cysts via Reduced GGPPS Expression.Human mutation · 2026Article
- Association between renal function and simple renal cyst growth: a retrospective study.European journal of medical research · 2025Article
- Assessment of Incidental Renal Cysts in Adults Undergoing Abdominal CT for Non-urological Indications.Cureus · 2025Article
- Association of Kidney Cysts With Progressive CKD After Radical Nephrectomy.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024Observational
- Plasma proteome fingerprint in kidney diseases.Frontiers in molecular biosciences · 2024Article
- Decline in measured glomerular filtration rate is associated with simple renal cyst in Chinese patients with type 2 diabetes.Journal of diabetes investigation · 2024Article
- Simple renal cysts: no longer simple?The Korean journal of internal medicine · 2022Article
- Association of simple renal cysts with metabolic syndrome in adults.Frontiers in public health · 2022Article
- Relationship Between Sporadic Renal Cysts and Renal Function Detected by Isotope Renography in Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThe prevalence of simple renal cysts increases with age; however, they are occasionally found in adults aged < 40 years. This cross-sectional study evaluated the clinical significance of simple cysts in young adults, focusing on their associations with hematuria and albuminuria.
methodsAdults aged < 40 years who underwent comprehensive medical examination between January 2005 and December 2013 were included. Simple renal cysts were identified by ultrasonography.
resultsRenal cysts were found in 276 of the 5,832 subjects (4.7%). Subjects with medullary sponge kidney (n = 1) or polycystic kidney disease (n = 5) were excluded. A single cyst and multiple cysts were found in 234 (4.0%) and 42 (0.7%) subjects, respectively. Age, high systolic blood pressure, and history of hypertension were independent risk factors for the presence of simple cysts. Simple cysts were not associated with an increased prevalence of hematuria. However, subjects with cysts showed a higher prevalence of albuminuria than those without (11.3% vs. 4.5%, p < 0.001). Multivariate analysis revealed that the existence of simple renal cysts was associated with a 2.30-fold increased prevalence of albuminuria (95% confidence interval, 1.512 to 3.519; p < 0.001) independent of other risk factors.
conclusionIn young adults, the presence of simple renal cysts was independently associated with an increased prevalence of albuminuria. The causal relationship needs to be elucidated in further studies.
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