ArticleThe Korean journal of internal medicine2022
Two-dimensional shear wave elastography for assessing liver fibrosis in patients with chronic liver disease: a prospective cohort study.
Article in The Korean journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 0 citations in OpenAlex.
- The Use of Ultrasound-Based Elastography Techniques in Liver Fibrosis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Intra-Observer Reproducibility of Endoscopic Ultrasound Point Shear-Wave Elastography: A 120-Patient Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Clinical impact of liver stiffness measurement on the prediction of surgical outcomes in hepatocellular carcinoma: which instrument performs better?Hepatobiliary surgery and nutrition · 2026Article
- Assessment of liver and spleen stiffness and hepatic steatosis by transient elastography (Fibroscan®) in type 1 Gaucher disease: a single center case-control cohort study.Orphanet journal of rare diseases · 2026Article
- Deep learning radiomics of elastography for diagnosing compensated advanced chronic liver disease: an international multicenter study.Visual computing for industry, biomedicine, and art · 2025Article
- From Liver to Kidney: The Overlooked Burden of Nonalcoholic Fatty Liver Disease in Chronic Kidney Disease.Journal of clinical medicine · 2025Review
- Modern ultrasound techniques for diagnosing liver steatosis and fibrosis: A systematic review with a focus on biopsy comparison.World journal of hepatology · 2025Article
- Liver Elastography for Liver Fibrosis Stratification: A Comparison of Three Techniques in a Biopsy-Controlled MASLD Cohort.Biomedicines · 2025Article
- Diagnostic performance of microvascular flow imaging for noninvasive assessment of liver fibrosis in chronic liver disease.PloS one · 2025Article
- Application of a quality threshold to improve liver shear wave elastography measurements in free-breathing pediatric patients.Ultrasonography (Seoul, Korea) · 2024Article
- Quality Assurance of Point and 2D Shear Wave Elastography through the Establishment of Baseline Data Using Phantoms.Sensors (Basel, Switzerland) · 2024Article
- Diagnostic performance of quantitative ultrasonography for hepatic steatosis in a health screening program: a prospective single-center study.Ultrasonography (Seoul, Korea) · 2024Article
- Advancements in metabolic-associated steatotic liver disease research: Diagnostics, small molecule developments, and future directions.Hepatology research : the official journal of the Japan Society of Hepatology · 2024Review
- Application and Diagnostic Performance of Two-Dimensional Shear Wave Elastography and Liver Fibrosis Scores in Adults with Class 3 Obesity.Nutrients · 2023Article
- Predicting symptomatic post-hepatectomy liver failure in patients with hepatocellular carcinoma: development and validation of a preoperative nomogram.European radiology · 2023Article
- Impact of Region-of-Interest Size on the Diagnostic Performance of Shear Wave Elastography in Differentiating Thyroid Nodules.Cancers · 2023Article
- The utility of two-dimensional shear wave elastography for predicting prostate cancer: a preliminary study.Ultrasonography (Seoul, Korea) · 2023Article
- A non-invasive test that enables longitudinal monitoring of chronic liver disease: VCTE versus 2D-SWE.The Korean journal of internal medicine · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND/
aimsThe objective of this study was to determine whether the newly developed two-dimensional shear wave elastography (2D-SWE, RS85, Samsung-shearwave imaging) was more valid and reliable than transient elastography (TE) for predicting the stage of liver fibrosis.
methodsThe study prospectively enrolled a total of 116 patients with chronic liver disease who underwent 2D-SWE, TE, laboratory testing, and liver biopsy on the same day from two tertiary care hospitals. One patient with unreliable measurement was excluded. The measurement of 2D-SWE was considered acceptable when a homogenous color pattern in a region of interest of at least 10 mm was detected at 10 different sites. Diagnostic performance was calculated using area under the receiver operating characteristic curve (AUROC).
resultsLiver fibrosis stages included F0 (18%), F1 (19%), F2 (24%), F3 (22%), and F4 (17%). Interclass correlation coefficient for inter-observer agreement in 2D-SWE was 0.994 (95% confidence interval [CI], 0.988 to 0.997). Overall, the results of 2D-SWE and stages of histological fibrosis were significantly correlated (r = 0.601, p < 0.001). For The 2D-SWE showed good diagnostic ability (AUROC, 0.851; 95% CI, 0.773 to 0.911) comparable to TE (AUROC, 0.859; 95% CI, 0.781 to 0.916) for the diagnosis of significant fibrosis (≥ F2), and the cut-off value was 5.8 kPa. AUROC and optimal cut-off of 2D-SWE for the diagnosis of liver cirrhosis were 0.889 (95% CI, 0.817 to 0.940) and 9.6 kPa, respectively. TE showed similar diagnostic performance in distinguishing cirrhosis (AUROC, 0.938; 95% CI, 0.877 to 0.974; p = 0.08).
conclusion2D-SWE is comparable to TE in diagnosing significant fibrosis and liver cirrhosis with high reliability.
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