Evidence map›Paper›PMID 34865221›Full record

ArticleBritish journal of haematology2022

The evolution of the loss of life expectancy in patients with chronic myeloid leukaemia: a population-based study in the Netherlands, 1989-2018.

Carolien C H M Maas, David van Klaveren, Geneviève I C G Ector, Eduardus F M Posthuma, Otto Visser, Peter E Westerweel, Jeroen J W M Janssen, Nicole M A Blijlevens, Avinash G Dinmohamed

Abstract read
In one paragraph

Article in British journal of haematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolien C H M MaasDepartment of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0002-3867-2465
David van KlaverenDepartment of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0002-2096-606X
Geneviève I C G EctorDepartment of Hematology, Radboudumc, Nijmegen, the Netherlands.ORCID 0000-0002-1558-944X
Eduardus F M PosthumaDepartment of Internal Medicine, Reinier de Graaf Gasthuis, Delft, the Netherlands.
Otto VisserDepartment of Registration, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, the Netherlands.
Peter E WesterweelDepartment of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Jeroen J W M JanssenAmsterdam UMC, Location VUmc, Department of Hematology, Cancer Center Amsterdam, Amsterdam, the Netherlands.
Nicole M A BlijlevensDepartment of Hematology, Radboudumc, Nijmegen, the Netherlands.
Avinash G DinmohamedDepartment of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands.ORCID 0000-0002-4767-6716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies on the conditional life expectancy of patients with chronic myeloid leukaemia (CML) are lacking. Using data from the Netherlands Cancer Registry, we examined the life expectancy of patients with CML in the Netherlands diagnosed during 1989-2018. As of the early 2010s, the life expectancy of patients with CML who survived several years after diagnosis came narrowly close to the general population's life expectancy, regardless of age. This finding can essentially be ascribed to the introduction and broader application of tyrosine kinase inhibitors (TKIs) and provide optimism to patients with CML who can look forward to a near-normal life expectancy in a modern TKI era.

Indexed as

AdultFemaleHumansLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLife ExpectancyMaleMiddle AgedNetherlandsProtein Kinase InhibitorsSurvival AnalysisProtein Kinase Inhibitorschronic myeloid leukaemiaepidemiologyimatinibleukaemiamathematical modelling

Identifiers

PMID34865221
PMCPMC9300106

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.