SynthesisLa Radiologia medica2021
Delta radiomics: a systematic review.
Synthesis in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
138 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Pooled it
- Delta radiomics: an updated systematic review.La Radiologia medica · 2024Pooled it
- Artificial intelligence applied to image-guided radiation therapy (IGRT): a systematic review by the Young Group of the Italian Association of Radiotherapy and Clinical Oncology (yAIRO).La Radiologia medica · 2024Pooled it
- Current state of radiomics in pediatric neuro-oncology practice: a systematic review.Pediatric radiology · 2023Pooled it
- Systematic review of the radiomics quality score applications: an EuSoMII Radiomics Auditing Group Initiative.European radiology · 2023Pooled it
- Artificial intelligence with magnetic resonance imaging for prediction of pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Application of delta radiomics based on cone-beam computed tomography in predicting radiotherapy efficacy for nasopharyngeal carcinoma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- CT texture analysis and delta radiomics in predicting R0 resection after preoperative chemotherapy in resectable pancreatic ductal adenocarcinoma.Translational oncology · 2026Article
- Interpretable machine learning model integrating delta-radiomics enhances postoperative recurrence prediction in early-stage lung adenocarcinoma.Journal of thoracic disease · 2026Article
- Physics-Informed Multiscale Decoding of Tissue Microstructure: The Gray Level Affinity Metrics (GLAM) Framework.Journal of imaging informatics in medicine · 2026Article
- Prediction of pathological complete response to neoadjuvant therapy in breast cancer integrating intratumoral and peritumoral delta radiomics with clinical features: a study based on multiparametric MRI.BMC medical imaging · 2026Article
- A Novel Radiomics-Integrated Panel for Preoperative Stratification of Pancreatic Neuroendocrine Tumors (PNETs).Cancers · 2026Article
- CT-based interpretable delta-radiomics model for risk stratification of pulmonary ground-glass nodules: a multicentre study.Insights into imaging · 2026Article
- Habitat Analysis for Risk Prediction of Nasopharyngeal Carcinoma: A Comparative Study of Different MRI Sequences and Regional Combinations.Bioengineering (Basel, Switzerland) · 2026Article
- Imaging Biomarkers in Radiotherapy.Cancers · 2026Review
- Enhanced CT-Based Delta-Radiomics: Predicting Lymphovascular and Perineural Invasion in Rectal Cancer Preoperatively.Journal of imaging informatics in medicine · 2026Article
- An explainable imaging-clinical biomarker for non-small cell lung cancer prognostication based on normalised hotspot to centroid distance and [European journal of nuclear medicine and molecular imaging · 2026Article
- A practical 10-step recipe for conducting radiomic studies.European radiology experimental · 2026Review
- Preoperative radiomics models for predicting risks of distinct recurrence patterns in pancreatic ductal adenocarcinoma based on contrast enhanced CT.Scientific reports · 2026Article
- Predicting dynamic changes of Ki-67 in breast cancer after neoadjuvant therapy based on multi-phase DCE-MRI delta-radiomics.Frontiers in oncology · 2026Article
78 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRadiomics can provide quantitative features from medical imaging that can be correlated with various biological features and clinical endpoints. Delta radiomics, on the other hand, consists in the analysis of feature variation at different acquisition time points, usually before and after therapy. The aim of this study was to provide a systematic review of the different delta radiomics approaches.
methodsEligible articles were searched in Embase, PubMed, and ScienceDirect using a search string that included free text and/or Medical Subject Headings (MeSH) with three key search terms: "radiomics", "texture", and "delta". Studies were analysed using QUADAS-2 and the RQS tool.
resultsForty-eight studies were finally included. The studies were divided into preclinical/methodological (five studies, 10.4%); rectal cancer (six studies, 12.5%); lung cancer (twelve studies, 25%); sarcoma (five studies, 10.4%); prostate cancer (three studies, 6.3%), head and neck cancer (six studies, 12.5%); gastrointestinal malignancies excluding rectum (seven studies, 14.6%), and other disease sites (four studies, 8.3%). The median RQS of all studies was 25% (mean 21% ± 12%), with 13 studies (30.2%) achieving a quality score < 10% and 22 studies (51.2%) < 25%.
conclusionsDelta radiomics shows potential benefit for several clinical endpoints in oncology (differential diagnosis, prognosis and prediction of treatment response, and evaluation of side effects). Nevertheless, the studies included in this systematic review suffer from the bias of overall low quality, so that the conclusions are currently heterogeneous, not robust, and not replicable. Further research with prospective and multicentre studies is needed for the clinical validation of delta radiomics approaches.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.