Evidence map›Paper›PMID 34865045›Full record

ArticleJournal of animal science2022

Effects of supplementing low-protein diets with sodium dichloroacetate and glucose on growth performance, carcass traits, and meat quality of growing-finishing pigs.

Yetong Xu, Huiyuan Chen, Ke Wan, Kaifeng Zhou, Yongsheng Wang, Jigang Li, Zhiru Tang, Weizhong Sun, Liuting Wu, Rui An and 4 more

Open access · greenAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Yetong XuDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.ORCID 0000-0002-8077-5847
Huiyuan ChenDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Ke WanDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Kaifeng ZhouShandong Provincial Animal Husbandry General Station, Jinan 250002, P. R. China.
Yongsheng WangNutrition and Health Research Institute, COFCO, Beijing 102209, P. R. China.
Jigang LiChongqing Academy of Animal Sciences, Chongqing 500153, P. R. China.
Zhiru TangDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Weizhong SunDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Liuting WuDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Rui AnSichuan Academy of Animal Science, Chengdu, 610066, P. R. China.
Zhongxiang RenDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Qi DingDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Kaiyang LiangDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.
Zhihong SunDepartment of Animal Science and Technology, Laboratory for Bio-feed and Molecular Nutrition, Southwest University, Chongqing 400715, P. R. China.ORCID 0000-0002-3839-037X
Southwest University · CNChongqing Academy of Animal Science · CNShandong Province Animal Husbandry and Veterinary Bureau · CNSichuan Animal Science Academy · CN

Funding

Fundamental Research Funds for the Central Universities XDJK2019B014National Natural Science Foundation of China 31872370
6 · The paper itself

Abstract

The objective of this study was to evaluate the effects of supplementing low-protein diets with sodium dichloroacetate (DCA) and glucose on growth performance, carcass traits, and meat quality of growing-finishing pigs. A total of 80 crossbred (Duroc × Landrace × Large White) growing barrows (27 ± 0.4 kg body weight) were allocated randomly to one of the five treatments during three successive 4-wk periods. There were five diets in each phase. Diet 1 was the control diet with normal protein levels (CON) where protein levels in the three phases were 18%, 16.5%, and 15.5%, respectively. The dietary protein levels of Diets 2, 3, 4, and 5 (the low-protein diets, LP) were decreased by 4.5% compared to Diet 1. Additionally, Diets 3 and 4 were supplemented with an extra 120 mg/kg DCA (LP + DCA) or 1.8% glucose (LP + GLUC), respectively. Diet 5 was further supplemented with an extra 120 mg/kg DCA and 1.8% glucose (LP + DCA + GLUC). The LP + DCA diet increased the average daily weight gain of pigs compared to the CON and LP diet in phase 3 and the overall experimental period (P < 0.001). The LP diet reduced the gain:feed ratios of the pigs compared to the CON, LP + DCA, and LP + DCA + GLUC diets in phase 1 and the overall experimental period (P < 0.001). Furthermore, gain:feed ratios in LP + DCA and LP + DCA + GLUC groups did not differ from that of the CON group (P > 0.10). Pigs fed the LP + DCA diet had higher pH values of meat at 24 h post-mortem than the CON group (P < 0.05). The LP + DCA + GLUC diet increased the total protein content in the longissimus dorsi (LD) muscle of pigs, compared to the other dietary treatments (P < 0.05), and increased the Arg and Leu contents in the LD muscle compared to the LP + DCA diet (P < 0.05). Moreover, the LP + DCA diet induced a higher C18:1n9t percentage in the LD muscle of pigs compared to other groups (P < 0.05). In conclusion, an LP diet reduced the feed efficiency in pigs and barely affected meat quality, whereas 120 mg/kg DCA supplementation in an LP diet improved the growth performance of growing-finishing pigs, showed modest effects on carcass traits, and improved the muscle protein content with the addition of glucose.

Indexed as

Animal FeedDiet, Protein-RestrictedAnimalsBody CompositionDichloroacetic AcidDietGlucoseMeatSwineDichloroacetic AcidGlucosegrowth performancelow-protein dietmeat qualitypigssodium dichloroacetate

Identifiers

PMID34865045
PMCPMC8722760
OpenAlexW4200424257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.