ArticleJournal of addiction medicine
Thematic Analysis of Reddit Content About Buprenorphine-naloxone Using Manual Annotation and Natural Language Processing Techniques.
Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Curation and Extraction of Drug-Related Entities from Reddit Platform.Proceedings. IEEE International Conference on Healthcare Informatics · 2026Article
- Informal caregiver uncertainty: exploring the presence of uncertainty in eating disorder Reddit posts.Journal of eating disorders · 2025Article
- Self-Disclosure and Social Support in a Web-Based Opioid Recovery Community: Machine Learning Analysis.JMIR formative research · 2025Article
- Social Listening for Patient Experiences With Stopping Extended-Release Buprenorphine: Content Analysis of Reddit Messages.Journal of medical Internet research · 2025Article
- Self-Reported Advantages and Disadvantages of Online Networking About Opioid Misuse Among Those Who Have or Are Currently Misusing Opioids.Substance use & misuse · 2025Article
- Large-Scale Analysis of Online Questions Related to Opioid Use Disorder on Reddit.Proceedings of the ... International AAAI Conference on Weblogs and Social Media. International AAAI Conference on Weblogs and Social Media · 2025Article
- The Use of Natural Language Processing Methods in Reddit to Investigate Opioid Use: Scoping Review.JMIR infodemiology · 2024Article
- Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms.Psychopharmacology · 2024Article
- Reduced speech coherence in psychosis-related social media forum posts.Schizophrenia (Heidelberg, Germany) · 2024Article
- First-hand accounts of structural stigma toward people who use opioids on Reddit.Social science & medicine (1982) · 2024Article
- Public Perceptions About Monkeypox on Twitter: Thematic Analysis.JMIR formative research · 2023Article
- Investigating Substance Use via Reddit: Systematic Scoping Review.Journal of medical Internet research · 2023Article
- Automatic Detection of Intimate Partner Violence Victims from Social Media for Proactive Delivery of Support.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023Article
- Barriers to opioid use disorder treatment: A comparison of self-reported information from social media with barriers found in literature.Frontiers in public health · 2023Article
- Signals of increasing co-use of stimulants and opioids from online drug forum data.Harm reduction journal · 2022Article
- Identifying and Characterizing Medical Advice-Seekers on a Social Media Forum for Buprenorphine Use.International journal of environmental research and public health · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOpioid use disorder (OUD) is a major public health crisis for which buprenorphine-naloxone is an effective evidence-based treatment. Analysis of Reddit data yields detailed information about firsthand experiences with buprenorphine-naloxone that has the potential to inform treatment of OUD.
methodsWe conducted a thematic analysis of posts about buprenorphine-naloxone from a Reddit forum in which Reddit users anonymously discuss topics related to opioid use. We used an application programming interface to retrieve posts about buprenorphine-naloxone, then applied natural language processing to generate meta-information and curate samples of salient posts. We manually categorized posts according to their content and conducted natural language processing-aided analysis of posts about buprenorphine tapering strategies, withdrawal symptoms, and adjunctive substances/behaviors useful in the tapering process.
resultsA total of 16,146 posts from 1933 redditors were retrieved from the /r/suboxone subreddit. Thematic analysis of sample posts (N = 200) revealed descriptions of personal experiences (74%), nonpersonal accounts (24%), and other content (2%). Among redditors who reported tapering to termination (N = 40), 0.063 mg and 0.125 mg were the most common termination doses. Fatigue, gastrointestinal disturbance, and mood disturbance were the most frequent adverse effects, and loperamide and vitamins/dietary supplements the most frequently discussed adverse effects adjunctive substances/behaviors respectively.
conclusionsDiscussions on Reddit are rich in information about buprenorphine-naloxone. Information derived from analysis of Reddit posts about buprenorphine-naloxone may not be available elsewhere and may help providers improve treatment of people with OUD through better understanding of the experiences of people who have used buprenorphine-naloxone.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.