Evidence map›Paper›PMID 34864701›Full record

ArticleJournal of pediatric rehabilitation medicine2021

Scope of care in the first four years of life for individuals born with myelomeningocele: A single institution experience1.

Betsy Hopson, Isaac Shamblin, Kathrin Zimmerman, Brandon Rocque, Arsalaan Salehani, Jeffrey P Blount

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05935631 (Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05935631 nacompletednot on this mapstarted 2023, after this paper: background citation

Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2023 to 2023Enrolled32ConditionsNeural Tube Defects, Folic Acid Deficiency, FortificationArmsSalt with folic acid and iodine
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. A global survey of neurosurgeons' awareness of neural tube defect prevalence, prevention strategies, and their clinical time allocation to spina bifida care.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  2. Article
  3. Evaluation of multidisciplinary high-risk pregnancy clinic for myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  4. What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Betsy HopsonDepartment of Neurosurgery, Division of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
Isaac ShamblinDepartment of Neurosurgery, Division of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
Kathrin ZimmermanDepartment of Neurosurgery, Division of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
Brandon RocqueDepartment of Neurosurgery, Division of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
Arsalaan SalehaniDepartment of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Jeffrey P BlountDepartment of Neurosurgery, Division of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · US

Funding

NCBDD CDC HHS U01 DD000773
6 · The paper itself

Abstract

purposeChildren with myelomeningocele are known to be consumers of substantial healthcare resources, with many early hospital encounters. The purpose of this study was to survey the extent of medical and surgical care that patients with myelomeningocele receive during the first four years of life.

methodsClinical and demographic data were collected on newborn infants with open myelomeningocele from the Children's of Alabama Spina Bifida Web Tracker, a prospective, comprehensive spina bifida database. Additional data pertaining to all hospital admissions, surgical procedures, and clinic visits were collected from the medical record.

resultsOne hundred and fourteen subjects with a primary diagnosis of myelomeningocele between 2004 and 2015 were included. Males slightly predominated (55%), 61.4% were Caucasian, 11% Hispanic/Latino; 28% had a mid-lumbar functional lesion level. Over the first four years of life, 688 total surgical procedures were performed (an average of 86 per child): 438 in year 1, 100 in year 2, 84 in year 3, and 66 in year 4. The mean number of hospital visits was 40.5. Total average drive time per patient over 4 years being 103.8 hours. Average number of nights spent in the hospital was 51.

conclusionChildren with myelomeningocele need multiple hospitalizations, surgeries, and medical encounters in the first 4 years of life. These data will be valuable when counselling new parents and prospective parents of children with this condition.

Indexed as

MeningomyeloceleSpinal DysraphismChildHumansInfantInfant, NewbornMaleProspective StudiesSurveys and QuestionnairesWhite Peoplemyelomeningocelepediatricsscope of careSpina bifida

Identifiers

PMID34864701
PMCPMC9003993
OpenAlexW3215026975

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.