Evidence map›Paper›PMID 34864688›Full record

ArticleJournal of Parkinson's disease2022

Taking the Time to Assess Cognition in Parkinson's Disease: The Clock Drawing Test.

Hemant Srivastava, Allen Joop, Raima A Memon, Jennifer Pilkington, Kimberly H Wood, Marissa Natelson Love, Amy W Amara

Open access · greenAbstract read
In one paragraph

Article in Journal of Parkinson's disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hemant SrivastavaDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Allen JoopDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Raima A MemonDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Jennifer PilkingtonDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Kimberly H WoodDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Marissa Natelson LoveDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
Amy W AmaraDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · US

Funding

The Effect of Low Frequency STN DBS on Sleep and Vigilance in PD PatientsK23NS080912 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AMARA, AMY WILLIS · 2012 to 2016
$934k
NINDS NIH HHS K23 NS080912
6 · The paper itself

Abstract

backgroundCognitive impairment is common and disabling in Parkinson's disease (PD). Cognitive testing can be time consuming in the clinical setting. One rapid test to detect cognitive impairment in non-PD populations is the Clock Drawing Test (CDT), which calls upon the brain's executive and visuospatial abilities to draw a clock designating a certain time.

objectiveTest the hypothesis that PD participants would perform worse on CDT compared to controls and that CDT would correlate with other measures of cognition.

methodsThis study evaluated two independent CDT scoring systems and differences in CDT performance between PD (N = 97) and control (N = 54) participants using a two-sample t-test. Pearson's correlations were conducted between the CDT and tests of sleepiness (Epworth Sleepiness Scale) and vigilance (Psychomotor Vigilance Test); executive function (Trails B-A); and global cognition (Montreal Cognitive Assessment). Receiver operating characteristic curves were used to determine cut points on the CDT that identify individuals who need additional cognitive testing.

resultsPD participants had worse performance on CDT compared to controls. The CDT was correlated with executive function (Trails B-A) and global cognition (Montreal Cognitive Assessment). The CDT correlated with vigilance (Psychomotor Vigilance Task) only in healthy controls. However, the CDT was not correlated with measures of sleepiness (Epworth Sleepiness Scale) in either group. A cut point of 9 on the Rouleau scale and 18 on the Mendez scale identified PD participants with cognitive impairment.

conclusionThe CDT is a rapid clinical cognitive assessment that is feasible in PD and correlates with other measures of cognition.

Indexed as

Cognitive DysfunctionParkinson DiseaseCognitionHumansNeuropsychological TestsSleepinessClock drawing testcognitionparkinson’s disease

Identifiers

PMID34864688
PMCPMC10913933
OpenAlexW3216698408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.