Evidence map›Paper›PMID 34864571›Full record

ArticleJournal of the mechanical behavior of biomedical materials2022

Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin.

Jungsil Kim, Austin J Cocciolone, Marius C Staiculescu, Robert P Mecham, Jessica E Wagenseil

Open access · greenAbstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Inverse finite element identification of murine aortic material properties:Computer methods in biomechanics and biomedical engineering · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Elastin, arterial mechanics, and stenosis.American journal of physiology. Cell physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jungsil KimDepartment of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO, USA.
Austin J CoccioloneDepartment of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Marius C StaiculescuDepartment of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO, USA.
Robert P MechamDepartment of Cell Biology and Physiology, Washington University, St. Louis, MO, USA.
Jessica E WagenseilDepartment of Mechanical Engineering and Materials Science, Washington University, St. Louis, MO, USA. Electronic address: jessica.wagenseil@wustl.edu.
Washington University in St. Louis · US

Funding

ASSEMBLY OF LUNG ELASTINR37HL053325 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P. · 2000 to 2009
$4.1M
ASSEMBLY OF LUNG ELASTINR01HL053325 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P. · 1995 to 2019
$3.6M
VESSEL STIFFENING, HYPERTENSION, AND VASCULAR EXTRACELLULAR MATRIXR01HL105314 · NHLBI · WASHINGTON UNIVERSITY · PI MECHAM, ROBERT P., WAGENSEIL, JESSICA · 2010 to 2018
$3.2M
BIOMECHANICAL FACTORS IN CONGENITAL VASCULAR DISEASER01HL115560 · NHLBI · WASHINGTON UNIVERSITY · PI WAGENSEIL, JESSICA · 2012 to 2015
$1.5M
Elastin deposition and stenosis formation in the developing aortaR56HL152420 · NHLBI · WASHINGTON UNIVERSITY · PI WAGENSEIL, JESSICA · 2020 to 2020
$394k
NHLBI NIH HHS R01 HL053325NHLBI NIH HHS R01 HL105314NHLBI NIH HHS R01 HL115560NHLBI NIH HHS R37 HL053325NHLBI NIH HHS R56 HL152420
6 · The paper itself

Abstract

Aortic wall material properties are needed for computational models and for comparisons across developmental and disease states. There has been abundant work in comparing aortic material properties across disease states, but limited work across developmental states. We performed passive biaxial mechanical testing on newborn mouse aorta with (Eln

Indexed as

AortaElastinAnimalsAnimals, NewbornMiceMice, Inbred C57BLMice, KnockoutStress, MechanicalElastinAortaBiomechanicsConstitutive modelingElastinMaturation

Identifiers

PMID34864571
PMCPMC9808670
OpenAlexW3215507126

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.