ArticleJournal of the mechanical behavior of biomedical materials2022
Design considerations for piezoelectrically powered electrical stimulation: The balance between power generation and fatigue resistance.
Article in Journal of the mechanical behavior of biomedical materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Electrostrategies in orthopaedic research.Biomaterials translational · 2025Article
- Design considerations for piezocomposite materials for electrical stimulation in medical implants.Journal of medical engineering & technology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Quality and timing of bone healing from orthopedic surgeries, especially lumbar spinal fusion procedures, is problematic for many patients. To address this issue, clinicians often use electrical stimulation to improve surgery success rates and decrease healing time in patients with increased risk of pseudarthrosis, including smokers and diabetics. Current invasive electrical stimulation devices require an implantable battery and a second surgery for removal. Piezoelectric composites within an interbody implant generate sufficient power under physiologic loads to deliver pulsed electrical stimulation without a battery and have demonstrated promising preclinical bone growth and fusion success. The objective of the current study was to assess the power generation and fatigue resistance of three commercially manufactured piezocomposite configurations in a modified implant design to demonstrate efficacy as a robust biomaterial within osteogenic implants. The three configurations were electromechanically assessed under physiological lumbar loading conditions, and all configurations produced sufficient power to promote bone healing. Additionally, electrical and mechanical fatigue performance was assessed under high load, low cycle conditions. All configurations demonstrated runout with no gross mechanical failure and two configurations demonstrated electrical fatigue resistance. Future piezoelectric implant design decisions should be based on power generation needs to stimulate bone growth, as mechanical fatigue efficacy was proven for all piezocomposite configurations tested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.