Evidence map›Paper›PMID 34864288›Full record

ArticleNeuroImage. Clinical2022

Imaging the extent and location of spatiotemporally distributed epileptiform sources from MEG measurements.

Xiyuan Jiang, Shuai Ye, Abbas Sohrabpour, Anto Bagić, Bin He

Abstract read
In one paragraph

Article in NeuroImage. Clinical, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Magnetoencephalography for Epilepsy Presurgical Evaluation.Current neurology and neuroscience reports · 2024
    Review
  4. Article
  5. Multi-Modal Electrophysiological Source Imaging With Attention Neural Networks Based on Deep Fusion of EEG and MEG.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiyuan JiangDepartment of Biomedical Engineering, Carnegie Mellon University, USA.
Shuai YeDepartment of Biomedical Engineering, Carnegie Mellon University, USA.
Abbas SohrabpourDepartment of Biomedical Engineering, Carnegie Mellon University, USA.
Anto BagićUniversity of Pittsburgh Comprehensive Epilepsy Center (UPCEC), University of Pittsburgh Medical School, USA.
Bin HeDepartment of Biomedical Engineering, Carnegie Mellon University, USA. Electronic address: bhe1@andrew.cmu.edu.

Funding

Electrophysiological Source Imaging of Partial EpilepsyR01NS096761 · NINDS · UNIVERSITY OF MINNESOTA · PI HE, BIN · 2016 to 2025
$3.6M
Electrophysiological source imaging guided transcranial focused ultrasoundRF1MH114233 · NIMH · UNIVERSITY OF MINNESOTA · PI HE, BIN · 2017 to 2017
$2.4M
Treating pain in sickle cell disease by means of focused ultrasound neuromodulationU18EB029354 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI HE, BIN · 2019 to 2019
$2.0M
Characterization of in vivo neuronal and inter-neuronal responses to transcranial focused ultrasoundR01NS124564 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI HE, BIN · 2021 to 2021
$2.0M
Mind-body awareness training and brain-computer interfaceR01AT009263 · NCCIH · UNIVERSITY OF MINNESOTA · PI HE, BIN · 2016 to 2020
$2.0M
Spatio-temporal Dynamic Imaging of Seizure SourcesR01EB021027 · NIBIB · UNIVERSITY OF MINNESOTA · PI HE, BIN · 2016 to 2020
$1.3M
NCCIH NIH HHS R01 AT009263NIBIB NIH HHS R01 EB021027NIBIB NIH HHS U18 EB029354NIMH NIH HHS RF1 MH114233NINDS NIH HHS R01 NS096761NINDS NIH HHS R01 NS124564
6 · The paper itself

Abstract

Non-invasive MEG/EEG source imaging provides valuable information about the epileptogenic brain areas which can be used to aid presurgical planning in focal epilepsy patients suffering from drug-resistant seizures. However, the source extent estimation for electrophysiological source imaging remains to be a challenge and is usually largely dependent on subjective choice. Our recently developed algorithm, fast spatiotemporal iteratively reweighted edge sparsity minimization (FAST-IRES) strategy, has been shown to objectively estimate extended sources from EEG recording, while it has not been applied to MEG recordings. In this work, through extensive numerical experiments and real data analysis in a group of focal drug-resistant epilepsy patients' interictal spikes, we demonstrated the ability of FAST-IRES algorithm to image the location and extent of underlying epilepsy sources from MEG measurements. Our results indicate the merits of FAST-IRES in imaging the location and extent of epilepsy sources for pre-surgical evaluation from MEG measurements.

Indexed as

Drug Resistant EpilepsyEpilepsies, PartialEpilepsyBrainElectroencephalographyHumansMagnetic Resonance ImagingMagnetoencephalographyElectrophysiological source imaging (ESI)EpilepsyMagnetoencephalography (MEG)Source extent imaging

Identifiers

PMID34864288
PMCPMC8648830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.