Evidence map›Paper›PMID 34863528›Full record

ArticleAnnals of emergency medicine2022

Design and Implementation of an Agitation Code Response Team in the Emergency Department.

Ambrose H Wong, Jessica M Ray, Laura D Cramer, Taylor K Brashear, Christopher Eixenberger, Caitlin McVaney, Jeanie Haggan, Mark Sevilla, Donald S Costa, Vivek Parwani and 4 more

Open access · greenAbstract read
In one paragraph

Article in Annals of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

  1. Association between patient primary language, physical restraints, and intramuscular sedation in the emergency department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  2. Article
  3. Article
  4. Article
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  6. Strategies for optimal management of pediatric acute agitation in emergency settings.Journal of the American College of Emergency Physicians open · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Ambrose H WongDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT. Electronic address: wongambrose@gmail.com.
Jessica M RayDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Laura D CramerYale School of Medicine, Yale School of Public Health, Yale-New Haven Hospital, New Haven, CT.
Taylor K BrashearDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Christopher EixenbergerDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Caitlin McVaneyDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Jeanie HagganAdult Emergency Services, Yale-New Haven Hospital, New Haven, CT.
Mark SevillaAdult Emergency Services, Yale-New Haven Hospital, New Haven, CT.
Donald S CostaDepartment of Protective Services, Yale-New Haven Hospital, New Haven, CT.
Vivek ParwaniDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Andrew UlrichDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
James D DziuraDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Steven L BernsteinDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT; Geisel School of Medicine at Dartmouth, Hanover, NH.
Arjun K VenkateshDepartment of Emergency Medicine, Yale-New Haven Hospital, New Haven, CT.
Yale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Clinical Decision Support Tool to Assess Risk and Prevent Agitation EventsK23MH126366 · NIMH · YALE UNIVERSITY · PI WONG, AMBROSE H · 2021 to 2024
$883k
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863NIMH NIH HHS K23 MH126366
6 · The paper itself

Abstract

STUDY

objectiveAgitation, defined as excessive psychomotor activity leading to violent and aggressive behavior, is becoming more prevalent in the emergency department (ED) amidst a strained behavioral health system. Team-based interventions have demonstrated promise in promoting de-escalation, with the hope of minimizing the need for invasive techniques, like physical restraints. This study aimed to evaluate an interprofessional code response team intervention to manage agitation in the ED with the goal of decreasing physical restraint use.

methodsThis quality improvement study occurred over 3 phases, representing stepwise rollout of the intervention: (1) preimplementation (phase I) to establish baseline outcome rates; (2) design and administrative support (phase II) to conduct training and protocol design; and (3) implementation (phase III) of the code response team. An interrupted time-series analysis was used to compare trends between phases to evaluate the primary outcome of physical restraint orders occurring during the study period.

resultsWithin the 634,578 ED visits over a 5-year period, restraint use significantly declined sequentially over the 3 phases (1.1%, 0.9%, and 0.8%, absolute change -0.3% between phases I and III, 95% confidence interval [CI] -0.4% to 0.3%), which corresponded to a 27.3% proportionate decrease in restraint rates between phases I and III. For the interrupted time-series analysis, there was a significantly decreasing slope in biweekly restraints in phase II compared to phase I (slope, -0.05 restraints per 1,000 ED visits per 2-week period, 95% CI -0.07 to -0.03), which was sustained in an incremental fashion in phase III (slope, -0.05, 95% CI -0.07 to -0.02).

conclusionWith the implementation of a structured agitation code response team intervention combined with design and administrative support, a decreased rate of physical restraint use occurred over a 5-year period. Results suggest that investment in organizational change, along with interprofessional collaboration during the management of agitated patients in the ED, can lead to sustained reductions in the use of an invasive and potentially harmful measure on patients.

Indexed as

Emergency Service, HospitalRestraint, PhysicalHumansInterrupted Time Series AnalysisPsychomotor AgitationQuality Improvement

Identifiers

PMID34863528
PMCPMC9038629
OpenAlexW3215776635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.