Evidence map›Paper›PMID 34863335›Full record

ArticleThe Lancet. Respiratory medicine2022

Stimulating severe COVID-19: the potential role of GM-CSF antagonism.

Helen L Leavis, Frank L van de Veerdonk, Srinivas Murthy

Abstract readComment
In one paragraph

Article in The Lancet. Respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. COVID-19 Pneumonia and Cytokine Storm Syndrome.Advances in experimental medicine and biology · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Comparing the Cytokine Storms of COVID-19 and Pandemic Influenza.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Helen L LeavisDepartment of Rheumatology and Clinical Immunology, Utrecht University, University Medical Center Utrecht, Netherlands.
Frank L van de VeerdonkDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Srinivas MurthyFaculty of Medicine, University of British Columbia, Vancouver, BC V6H 3V4, Canada. Electronic address: srinivas.murthy@cw.bc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Granulocyte-Macrophage Colony-Stimulating FactorHumansSARS-CoV-2Granulocyte-Macrophage Colony-Stimulating Factor

Identifiers

PMID34863335
PMCPMC8635456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.