Evidence map›Paper›PMID 34863252›Full record

ArticleTrials2021

Impact of perinatal environmental health education intervention on exposure to endocrine disruptors during pregnancy-PREVED study: study protocol for a randomized controlled trial.

Houria El Ouazzani, Steeve Rouillon, Nicolas Venisse, Lynda Sifer-Rivière, Antoine Dupuis, Guillaume Cambien, Sarah Ayraud-Thevenot, Anne-Sophie Gourgues, Pascale Pierre-Eugène, Fabrice Pierre and 4 more

Erratum issued 2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03233984 nacompletednot on this map

Effect of an Environmental Health Education Program on Pregnant Women in Order to Reduce Endocrine Disruptor Exposition : Controled Randomized Trial on Primary Prevention

TypeinterventionalSponsorPoitiers University HospitalRan2017 to 2020Enrolled267ConditionsPregnancy, Endocrine System, Prevention ProgramArmssensibilisation program "Ma maison, mon environnement santé"
NCT07560579 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled226ConditionsObesity &Amp, Amp, Amp, OverweightArmsEducational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Houria El OuazzaniHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France. houria.el.fellah.el.ouazzani@univ-poitiers.fr.ORCID http://orcid.org/0000-0003-1021-7134
Steeve RouillonHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Nicolas VenisseHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Lynda Sifer-RivièreHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Antoine DupuisHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Guillaume CambienHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Sarah Ayraud-ThevenotHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Anne-Sophie GourguesHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Pascale Pierre-EugèneHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Fabrice PierreBioSPharm Pole, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Sylvie RabouanHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
DisProSE Group
Virginie MigeotHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Marion Albouy-LlatyHealth-Endocrine Disruptors-EXposome (HEDEX), INSERM-CIC1402, University Hospital of Poitiers, 2 rue de la Milétrie, 86021, Poitiers CEDEX, France.
Inserm · FRCentre National de la Recherche Scientifique · FRUniversité de Poitiers · FR

Funding

Fondation de France (FR) 784314908
6 · The paper itself

Abstract

backgroundThe suspected or actual effects on health of endocrine-disrupting chemicals (EDC) and their ubiquitous presence in everyday life justify the implementation of health promotion interventions. These interventions should ideally be applied during critical windows like pregnancy. Perinatal environmental health education interventions may help to reduce EDC exposure during pregnancy. METHODS/

designPREVED (Pregnancy, PreVention, Endocrine Disruptors) is an open-label randomized controlled trial assessing the impact of environmental health education intervention on EDC exposure during pregnancy. Inclusion, consent, and randomization take place during the first trimester. The participants are randomly allocated into three groups: (i) control group (information leaflet on EDCs), (ii) intervention group in neutral location (information leaflet and workshops in a meeting room), and (iii) intervention group in contextualized location (information leaflet and workshops in a real apartment). Workshops are organized between the second and third trimesters of pregnancy. Main outcome is the percentage of participants who reported consuming manufactured/industrial food. Secondary outcomes are as follows: (i) psycho-social dimensions, (ii) EDC concentrations in urine, (iii) EDC concentration in colostrum, and (iv) percentage of participants who reported consuming paraben-free personal care products. DISCUSSION: PREVED is a ground-breaking intervention research project dedicated to perinatal environmental health education that aims to identify pollutant sources in daily life and to offer accessible and realistic alternative solutions, by promoting the sharing of know-how and experience in a positive and non-alarmist approach.

trial registrationClinicalTrials.gov : NCT03233984 (current status: ongoing). Retrospectively registered on 31 July 2017 ( https://clinicaltrials.gov/ct2/show/NCT03233984 ) because when the first participant was enrolled in this non-drug intervention, ClinicalTrials.gov was centered in therapeutic trials. The World Health Organization Trial Registration Data Set is in Additional file 1.

Indexed as

Endocrine DisruptorsEnvironmental HealthFemaleHealth EducationHumansPregnancyRandomized Controlled Trials as TopicEndocrine DisruptorsEndocrine disruptorsEnvironmental healthIntervention researchMaternal exposurePregnancyRandomized controlled trial

Identifiers

PMID34863252
PMCPMC8642981
OpenAlexW4200583284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.