Evidence map›Paper›PMID 34863220›Full record

SynthesisImplementation science : IS2021

Use and effects of implementation strategies for practice guidelines in nursing: a systematic review.

Christine E Cassidy, Margaret B Harrison, Christina Godfrey, Vera Nincic, Paul A Khan, Patricia Oakley, Amanda Ross-White, Hilary Grantmyre, Ian D Graham

Abstract readSystematic Review
In one paragraph

Synthesis in Implementation science : IS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  13. Pressure ulcer practice in European hospitals: a scoping review.International journal of nursing studies advances · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christine E CassidySchool of Nursing, Dalhousie University, 5860 University Ave., Halifax, NS, B3H 4R2, Canada. ccassidy@dal.ca.ORCID 0000-0001-7770-5058
Margaret B HarrisonSchool of Nursing, Queen's University, 92 Barrie Street, Kingston, ON, K7L 3J9, Canada.
Christina GodfreySchool of Nursing, Queen's University, 92 Barrie Street, Kingston, ON, K7L 3J9, Canada.
Vera NincicLi Ka Shing Knowledge Institute of St. Michael's Hospital, 209 Victoria Street, Toronto, ON, M5B 1W8, Canada.
Paul A KhanLi Ka Shing Knowledge Institute of St. Michael's Hospital, 209 Victoria Street, Toronto, ON, M5B 1W8, Canada.
Patricia OakleyNational Research Council Canada, Institute for Information Technology, 46 Dineen Drive, Fredericton, NB, E3B 9W4, Canada.
Amanda Ross-White, Queen's University Library, Queen's University, 18 Stuart Street, Kingston, ON, K7L 3N6, Canada.
Hilary GrantmyreSchool of Nursing, Dalhousie University, 5860 University Ave., Halifax, NS, B3H 4R2, Canada.
Ian D GrahamSchool of Epidemiology and Public HealthSchool of Nursing, University of Ottawa, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.

Funding

CIHR 143237
6 · The paper itself

Abstract

backgroundPractice guidelines can reduce variations in nursing practice and improve patient care. However, implementation of guidelines is complex and inconsistent in practice. It is unclear which strategies are effective at implementing guidelines in nursing. This review aimed to describe the use and effects of implementation strategies to facilitate the uptake of guidelines focused on nursing care.

methodsWe conducted a systematic review of five electronic databases in addition to the Cochrane Effective Practice and Organization of Care (EPOC) Group specialized registry. Studies were included if implementation of a practice guideline in nursing and process or outcome of care provided by nurses were reported. Two reviewers independently screened studies, assessed study quality, extracted data, and coded data using the EPOC taxonomy of implementation strategies. For those strategies not included in the EPOC taxonomy, we inductively categorized these strategies and generated additional categories. We conducted a narrative synthesis to analyze results.

resultsThe search identified 46 papers reporting on 41 studies. Thirty-six studies used a combination of educational materials and educational meetings. Review findings show that multicomponent implementation strategies that include educational meetings, in combination with other educational strategies, report positive effects on professional practice outcomes, professional knowledge outcomes, patient health status outcomes, and resource use/expenditures. Twenty-three of the 41 studies employed implementation strategies not listed within the EPOC taxonomy, including adaptation of practice guidelines to local context (n = 9), external facilitation (n = 14), and changes to organizational policy (n = 3). These implementation strategies also corresponded with positive trends in patient, provider, and health system outcomes.

conclusionsNursing guideline implementation may benefit from using the identified implementation strategies described in this review, including participatory approaches such as facilitation, adaptation of guidelines, and organizational policy changes. Further research is needed to understand how different implementation strategy components work in a nursing context and to what effect. As the field is still emerging, future reviews should also explore guideline implementation strategies in nursing in quasi or non-experimental research designs and qualitative research studies.

Indexed as

Qualitative ResearchHumansClinical practice guidelinesImplementationImplementation strategiesNursingSystematic review

Identifiers

PMID34863220
PMCPMC8642950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.