ReviewClinical neurology and neurosurgery2022
Understanding the genetics of intracranial aneurysms: A primer.
Review in Clinical neurology and neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Achievement and Future Prospectives from Translational Research Targeting Intracranial Aneurysm.Neurologia medico-chirurgica · 2026Review
- Intracranial aneurysms as a manifestation of premature vascular aging: Cellular senescence, inflammaging, and wall degeneration.Ageing research reviews · 2026Review
- De novo ruptured intracranial aneurysm associated with cerebral proliferative angiopathy: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Bilateral infraoptic anterior cerebral artery associated with de novo aneurysm formation over a 10-year period: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Fatal Triad of Subarachnoid Hemorrhage, Cervical Hematoma, and Upper Airway Obstruction in a Patient With Neurofibromatosis Type 1: A Case Report.Critical care explorations · 2025Article
- Perianeurysmal edema after coil embolization of a giant ruptured aneurysm: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- The diagnostic and prognostic value of miR-188-5p in intracranial aneurysm (IA) and its potential regulatory mechanism.Hereditas · 2025Article
- A ruptured de novo anastomotic aneurysm shortly after superficial temporal artery-to-middle cerebral artery bypass surgery in a patient with moyamoya disease: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Endovascular treatment for a symptomatic dissecting ophthalmic artery aneurysm occurring in the orbit: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Time to Consider Pharmacologic Management of Unruptured Intracranial Aneurysms?Journal of stroke · 2025Review
- The causal association between 91 inflammatory Circulating proteins and intracerebral hemorrhage: A bidirectional two-sample Mendelian randomization study.Neurosurgical review · 2025Article
- Article
- Circulating immune cell landscape and T-cell abnormalities in patients with moyamoya disease.Clinical and translational medicine · 2024Article
- S100A9 aggravates early brain injury after subarachnoid hemorrhage via inducing neuroinflammation and inflammasome activation.iScience · 2024Article
- Risk factors and predictive indicators of rupture in cerebral aneurysms.Frontiers in physiology · 2024Review
- Role and mechanisms of mast cells in brain disorders.Frontiers in immunology · 2024Review
- Cerebral Aneurysms Caused by Atrial Myxoma-A Systematic Review of the Literature.Journal of personalized medicine · 2022Review
- Comparison of Sex Differences in Outcomes of Patients With Aneurysmal Subarachnoid Hemorrhage: A Single-Center Retrospective Study.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
Abstract
The genetics of intracranial aneurysms is complex. Much work has been done looking at the extracellular matrix surrounding cerebral vasculature as well as the role of matrix metalloproteinases. This comprehensive review summarizes what is known to date about the important genetic components that predispose to aneurysm formation and critically discusses the published findings. We discuss promising pre-clinical models of aneurysm formation and subarachnoid hemorrhage, and highlight avenues for future discovery, while considering limitations in the research to date. This review will further serve as a comprehensive reference guide to understand the genetic underpinnings for aneurysm pathophysiology and act as a primer for further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.