Evidence map›Paper›PMID 34863037›Full record

ArticleEuropean journal of endocrinology2022

European Expert Consensus on Practical Management of Specific Aspects of Parathyroid Disorders in Adults and in Pregnancy: Recommendations of the ESE Educational Program of Parathyroid Disorders.

Jens Bollerslev, Lars Rejnmark, Alexandra Zahn, Ansgar Heck, N M Appelman-Dijkstra, Luis Cardoso, Fadil M Hannan, Filomena Cetani, Tanja Sikjær, Anna Maria Formenti and 26 more

Open access · hybridAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 7 pooled it
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 7 syntheses or guidelines pooled it, 192 citations in OpenAlex.

  1. Pooled it
  2. Guideline
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  5. Italian Guidelines for the Management of Sporadic Primary Hyperparathyroidism.Endocrine, metabolic & immune disorders drug targets · 2024
    Guideline
  6. Pooled it
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  8. Trial
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  10. Review
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  15. Comparative performance ofEuropean journal of nuclear medicine and molecular imaging · 2026
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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 14 countries.

Jens BollerslevJ Bollerslev, Section of Specialized Endocrinology, Department of Endocrinology, Medical Clinic, Oslo University Hospital, Oslo, Norway.
Lars RejnmarkL Rejnmark, Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, 8000, Denmark.
Alexandra ZahnA Zahn, Department of Endocrine Surgery, Schön Klinik Hamburg-Eilbek, Hamburg, Germany.
Ansgar HeckA Heck, Section for Specialised Endocrinology, Department of Endocrinology, Medical Clinic, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
N M Appelman-DijkstraN Appelman-Dijkstra, Department of Medicine; Division of Endocrinology, LUMC, Leiden, Netherlands.
Luis CardosoL Cardoso, Instituto de Investigação e Inovação em Saúde da Universidade do Porto, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Portugal.
Fadil M HannanF Hannan, Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom of Great Britain and Northern Ireland.
Filomena CetaniF Cetani, Endocrinology and Metabolism, University of Pisa, Pisa, 56124, Italy.
Tanja SikjærT Sikjær, Department of Endocrinology and Internal Medicine, Aarhus Universitetshospital, Aarhus, Denmark.
Anna Maria FormentiA Formenti, Institute of Endocrine and Metabolic Sciences, Vita-Salute San Raffaele University, Milano, Italy.
Sigridur BjörnsdottirS Björnsdottir, Department of Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Camilla Schalin-JanttiC Schalin-Jantti, Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Zhanna BelayaZ Belaya, neuroendocrinology and bone disease, The National Research Center for Endocrinology, Moscow, 117036, Russian Federation.
Fraser Wilson GibbF Gibb, Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom of Great Britain and Northern Ireland.
Bruno LapauwB Lapauw, Endocrinology, Ghent University Hospital, Ghent, B-9000, Belgium.
Karin AmreinK Amrein, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Corinna WickeC Wicke, Thyroid Center, Luzerner Kantonsspital, Luzern, Switzerland.
Corinna GrasemannC Grasemann, Department of Pediatrics, Ruhr University of Bochum Faculty of Medicine, Bochum, Germany.
Michael KrebsM Krebs, Internal Medicine III, Div. Endocrinology, Medical University of Vienna, Vienna, 1090, Austria.
Eeva M RyhänenE Ryhänen, Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ozer MakayO Makay, general surgery, ege university, izmir, 35100, Turkey.
Salvatore MinisolaS Minisola, Department of Internal Medicine and Medical Disciplines, "Sapienza" University of Rome, Rome, 00161, Italy.
Sebastien GaujouxS Gaujoux, Digestive and Endocrine surgery, Hopital Cochin, Paris, France.
Jean-Philippe BertocchioJ Bertocchio, Nephrology department,, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Boulevard de l'Hôpital, 75013 Paris , France.
Zaki K Hassan-SmithZ Hassan-Smith, Department of Endocrinology; University Hospitals Birmingham, University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.
Agnès LinglartA Linglart, Pediatric endocrinology, APHP, Bicêtre Paris-Sud Hospital, Le Kremlin Bicetre, 94270, France.
Elizabeth M WinterE Winter, Department of Medicine; Division of Endocrinology, Leiden University Medical Center, Leiden, Netherlands.
Martina KollmannM Kollmann, Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria.
Hans-Georg ZmierczakH Zmierczak, Reference centre for rare bone, calcium and phosphate disorders, Ghent Universitary Hospital, Ghent, Belgium.
Elena TsourdiE Tsourdi, Division of Endocrinology, Diabetes, and Bone Diseases, Dresden Technical University Medical Center , Dresden, 01307, Germany.
Stefan PilzS Pilz, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.
Heide SiggelkowH Siggelkow, Endokrinologikum Göttingen, Georg-August-University Göttingen, Gottingen, Germany.
Neil J GittoesN Gittoes, Department of Endocrinology; University Hospitals Birmingham , University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.
Claudio MarcocciC Marcocci, Clinical and Experimental Medicine, University of Pisa, Pisa, 56124, Italy.
Peter KamenickyP Kamenicky, Centre de Référence des Maladies Rares de l'Hypophyse, Le Kremlin-Bicêtre, Île-de-France, France.
2021 PARAT Working Group
Medical University of Graz · ATAarhus University Hospital · DKGhent University Hospital · BELeiden University Medical Center · NLOslo University Hospital · NOUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Helsinki · FIUniversity of Pisa · ITDélégation Paris 5 · FREdinburgh Royal Infirmary · GBEge University · TREndokrinologikum · DEi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTInserm · FRKarolinska University Hospital · SELuzerner Kantonsspital · CHMedical University of Vienna · ATSapienza University of Rome · ITSchön Klinik Hamburg Eilbek · DESorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This European expert consensus statement provides recommendations for the diagnosis and management of primary hyperparathyroidism (PHPT), chronic hypoparathyroidism in adults (HypoPT), and parathyroid disorders in relation to pregnancy and lactation. Specified areas of interest and unmet needs identified by experts at the second ESE Educational Program of Parathyroid Disorders (PARAT) in 2019, were discussed during two virtual workshops in 2021, and subsequently developed by working groups with interest in the specified areas. PHPT is a common endocrine disease. However, its differential diagnosing to familial hypocalciuric hypercalcemia (FHH), the definition and clinical course of normocalcemic PHPT, and the optimal management of its recurrence after surgery represent areas of uncertainty requiring clarifications. HypoPT is an orphan disease characterized by low calcium concentrations due to insufficient PTH secretion, most often secondary to neck surgery. Prevention and prediction of surgical injury to the parathyroid glands are essential to limit the disease-related burden. Long-term treatment modalities including the place for PTH replacement therapy and the optimal biochemical monitoring and imaging surveillance for complications to treatment in chronic HypoPT, need to be refined. The physiological changes in calcium metabolism occurring during pregnancy and lactation modify the clinical presentation and management of parathyroid disorders in these periods of life. Modern interdisciplinary approaches to PHPT and HypoPT in pregnant and lactating women and their newborns children are proposed. The recommendations on clinical management presented here will serve as background for further educational material aimed for a broader clinical audience, and were developed with focus on endocrinologists in training.

Indexed as

HypercalcemiaHyperparathyroidism, PrimaryHypoparathyroidismParathyroid DiseasesAdultCalciumFemaleHumansInfant, NewbornLactationParathyroid HormonePregnancyCalciumParathyroid Hormone

Identifiers

PMID34863037
PMCPMC8789028
OpenAlexW4200018189

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.