ArticleThe New phytologist2022
FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses.
Article in The New phytologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 58 citations in OpenAlex.
- Regulatory Mechanisms Underlying Stem Strength and Toughness in Dicotyledonous Plants: Implications for Soybean Breeding.Current issues in molecular biology · 2026Review
- The BpFLA1 and BpFLA2 genes are involved in regulating secondary xylem development in Betula platyphylla and respond to artificial bending.Annals of botany · 2026Article
- A FnWRKY17-Frontiers in plant science · 2026Article
- A high spatial resolution transcriptomics of tension wood reveals the genetic program of contractile G-layer formation.Frontiers in plant science · 2026Article
- Pangenomic and Phenotypic Characterization of ColombianInternational journal of molecular sciences · 2025Article
- Genome-wide identification and analysis of the FLA gene family in maize (Zea mays L.) and its expression in response to abiotic stresses.BMC plant biology · 2025Article
- MdDSK2a-Like-MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ectopic expression of wax ester synthase under a wood-specific promoter enhances cell wall production and wood hydrophobicity.Biotechnology for biofuels and bioproducts · 2025Article
- Phenotypic and transcriptomic analysis reveals key genes associated with plant height in rubber tree and functional characterization of the candidate gene HbFLA11.The plant genome · 2025Article
- Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development.Nature communications · 2025Article
- Genetic linkage analysis of stable QTLs in Gossypium hirsutum RIL population revealed function of GhCesA4 in fiber development.Journal of advanced research · 2024Article
- Expression of dehydroshikimate dehydratase in poplar induces transcriptional and metabolic changes in the phenylpropanoid pathway.Journal of experimental botany · 2024Article
- Discovery of genes that positively affect biomass and stress associated traits in poplar.Frontiers in plant science · 2024Article
- Morphological, histological and transcriptomic mechanisms underlying different fruit shapes inPeerJ · 2024Article
- Leveraging transcriptomics-based approaches to enhance genomic prediction: integrating SNPs and gene networks for cotton fibre quality improvement.Frontiers in plant science · 2024Article
- GWAS identifies candidate genes controlling adventitious rooting inHorticulture research · 2023Article
- Distinct functions of FASCILIN-LIKE ARABINOGALACTAN PROTEINS relate to domain structure.Plant physiology · 2023Article
- Comparison of Tomato Transcriptomic Profiles Reveals Overlapping Patterns in Abiotic and Biotic Stress Responses.International journal of molecular sciences · 2023Article
- Review
- Recurrent symmetrical bendings cause dwarfing inFrontiers in plant science · 2023Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Secondary cell walls (SCWs) in stem xylem vessel and fibre cells enable plants to withstand the enormous compressive forces associated with upright growth. It remains unclear if xylem vessel and fibre cells can directly sense mechanical stimuli and modify their SCW during development. We provide evidence that Arabidopsis SCW-specific Fasciclin-Like Arabinogalactan-proteins 11 (FLA11) and 12 (FLA12) are possible cell surface sensors regulating SCW development in response to mechanical stimuli. Plants overexpressing FLA11 (OE-FLA11) showed earlier SCW development compared to the wild-type (WT) and altered SCW properties that phenocopy WT plants under compression stress. By contrast, OE-FLA12 stems showed higher cellulose content compared to WT plants, similar to plants experiencing tensile stress. fla11, OE-FLA11, fla12, and OE-FLA12 plants showed altered SCW responses to mechanical stress compared to the WT. Quantitative polymerase chain reaction (qPCR) and RNA-seq analysis revealed the up-regulation of genes and pathways involved in stress responses and SCW synthesis and regulation. Analysis of OE-FLA11 nst1 nst3 plants suggests that FLA11 regulation of SCWs is reliant on classical transcriptional networks. Our data support the involvement of FLA11 and FLA12 in SCW sensing complexes to fine-tune both the initiation of SCW development and the balance of lignin and cellulose synthesis/deposition in SCWs during development and in response to mechanical stimuli.
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