Evidence map›Paper›PMID 34862819›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2022

17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children.

Jessica D Gereige, Andreanne Morin, Agustin Calatroni, Cynthia M Visness, Robert A Wood, Meyer Kattan, Leonard B Bacharier, Patrice Becker, Matthew C Altman, James E Gern and 2 more

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The role of epigenetics in multi-generational transmission of asthma: An NIAID workshop report-based narrative review.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Review
  5. New Insights Relating Gasdermin B to the Onset of Childhood Asthma.American journal of respiratory cell and molecular biology · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Jessica D GereigeDepartment of Medicine, Division of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0003-0755-1131
Andreanne MorinDepartment of Human Genetics, University of Chicago, Chicago, Illinois, USA.
Agustin CalatroniRho, Inc. Federal Research Operations, Durham, North Carolina, USA.
Cynthia M VisnessRho, Inc. Federal Research Operations, Durham, North Carolina, USA.
Robert A WoodDepartment of Pediatrics, Johns Hopkins University, Baltimore, Maryland, USA.
Meyer KattanDepartment of Pediatrics, Columbia University, New York City, New York, USA.
Leonard B BacharierMonroe Carell Jr. Children's Hospital at Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Patrice BeckerNational Institute of Allergy and Infectious Disease, Bethesda, Maryland, USA.
Matthew C AltmanBenaroya Research Institute, Systems Immunology Division, Seattle, Washington, USA.
James E GernDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.ORCID 0000-0002-6667-4708
Carole OberDepartment of Human Genetics, University of Chicago, Chicago, Illinois, USA.
George T O'ConnorDepartment of Medicine, Division of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Boston University · USRho (United States) · USUniversity of Chicago · USCity University of New York · USJohns Hopkins University · USMonroe Carell Jr. Children's Hospital · USNational Institute of Allergy and Infectious Diseases · USUniversity of Washington · USUniversity of Wisconsin–Madison · US

Funding

Transplantation GroupUM2AI117870 · NIAID · RHO FEDERAL SYSTEMS DIVISION, INC. · PI DAVID, GLORIA · 2015 to 2023
$208.1M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Inner City Asthma consortium 3 (ICAC3)UM1AI114271 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E., JACKSON, DANIEL J · 2014 to 2021
$79.4M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
RhoFED AA-SCCCU01AI178772 · NIAID · RHO FEDERAL SYSTEMS DIVISION, INC. · PI Gloria David, Cynthia M Visness · 2023 to 2026
$37.2M
BIOLOGY OF THE LUNG--MULTIDISCIPLINARY PROGRAMT32HL007035 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Darrell N. Kotton, JOSEPH P MIZGERD · 1985 to 2026
$24.3M
Inner-City Asthma Consortium-266025496-266025496N01AI025496 · NIAID · UNIVERSITY OF WISCONSIN · PI BUSSE, WILLIAM · 2002 to 2006
–
NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001430NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002345NHLBI NIH HHS T32 HL007035NIAID NIH HHS HHSN272200900052CNIAID NIH HHS N01 AI025482NIAID NIH HHS N01 AI025496NIAID NIH HHS U01 AI178772NIAID NIH HHS UM1 AI114271NIAID NIH HHS UM2 AI117870NIH HHS UH3 OD023282
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaChildEnvironmental ExposureGenetic Predisposition to DiseaseHumans17q12-q21 asthma locusallergen exposureasthmacommon coldgenotype-exposure interactionGSDMAurban environment

Identifiers

PMID34862819
PMCPMC10829392
OpenAlexW3215442063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.