Evidence map›Paper›PMID 34862748›Full record

ArticleCNS neuroscience & therapeutics2022

Suppression of P2X3 receptor-mediated currents by the activation of α

Jia-Wei Hao, Wen-Long Qiao, Qing Li, Shuang Wei, Ting-Ting Liu, Chun-Yu Qiu, Wang-Ping Hu

Open access · goldAbstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Endogenous forms of ATP-ATPProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia-Wei HaoSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Wen-Long QiaoSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Qing LiSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Shuang WeiSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Ting-Ting LiuSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Chun-Yu QiuSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.
Wang-Ping HuSchool of Basic Medical Sciences, Hubei University of Science and Technology, Hubei, China.ORCID 0000-0003-1870-325X
Hubei University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe α

methodsElectrophysiological recordings were carried out on rat DRG neurons, and nociceptive behavior was quantified in rats.

resultsThe activation of α

conclusionsThese results suggested that activation of α

Indexed as

Adrenergic alpha-2 Receptor AgonistsAnimalsBehavior, AnimalDexmedetomidineElectrophysiological PhenomenaGanglia, SpinalMaleNociceptionRatsRats, Sprague-DawleyReceptors, Adrenergic, alpha-2Receptors, Purinergic P2X3Adra2a protein, ratAdrenergic alpha-2 Receptor AgonistsDexmedetomidineReceptors, Adrenergic, alpha-2Receptors, Purinergic P2X3currentdorsal root ganglion neuronnociceptive behaviorP2X3 receptorα2A adrenoceptor

Identifiers

PMID34862748
PMCPMC8739037
OpenAlexW3217736100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.