ReviewOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2022
Binocular visual function and fixational control in patients with macular disease: A review.
Review in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Transcranial Direct Current Stimulation Does Not Enhance Perceptual Learning of Chinese Character Reading in Adults With Macular Degeneration.Investigative ophthalmology & visual science · 2026Trial
- Interocular Differences in Visual Acuity and Refractive Status Between Unilateral Early and Late Age-Related Macular Degeneration: A Nationwide Population-Based Study.Journal of clinical medicine · 2026Article
- Article
- The effects of unilateral deprivation amblyopia on fixation stability.Frontiers in neuroscience · 2026Article
- Examining oculomotor behavior in central vision loss with a gaze-contingent display.bioRxiv : the preprint server for biology · 2025Article
- Retinal Autophagy for Sustaining Retinal Integrity as a Proof of Concept for Age-Related Macular Degeneration.International journal of molecular sciences · 2025Review
- Biofeedback rehabilitation in patients with binocular inhibition due to macular disease.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Intraocular lens power calculation in pediatric cataract surgery: A narrative review.Medicine · 2025Review
- Long Term Visual Outcomes of an Extended Macular Vision IOL in Eyes with Macular Disease and Visually Insignificant Cataract.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Visual function and biofeedback training of patients with central vision loss: a review.International journal of ophthalmology · 2023Review
- Binocularity Principles of PRL Development in Patients With Macular Disease.Investigative ophthalmology & visual science · 2022Article
- Binocular visual function and fixational control in patients with macular disease: A review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For normally sighted observers, the centre of the macula-the fovea-provides the sharpest vision and serves as the reference point for the oculomotor system. Typically, healthy observers have precise oculomotor control and binocular visual performance that is superior to monocular performance. These functions are disturbed in patients with macular disease who lose foveal vision. An adaptation to central vision loss is the development of a preferred retinal locus (PRL) in the functional eccentric retina, which is determined with a fixation task during monocular viewing. Macular disease often affects the two eyes unequally, but its impact on binocular function and fixational control is poorly understood. Given that patients' natural viewing condition is binocular, the aim of this article was to review current research on binocular visual function and fixational oculomotor control in macular disease. Our findings reveal that there is no overall binocular gain across a range of visual functions, although clear evidence exists for subgroups of patients who exhibit binocular summation or binocular inhibition, depending on the clinical characteristics of their two eyes. The monocular PRL of the better eye has different characteristics from that of the worse eye, but during binocular viewing the PRL of the better eye drives fixational control and may serve as the new reference position for the oculomotor system. We conclude that evaluating binocular function in patients with macular disease reveals important clinical aspects that otherwise cannot be determined solely from examining monocular functions, and can lead to better disease management and interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.