Evidence map›Paper›PMID 34862410›Full record

ArticleScientific reports2021

Differentiating features of OCT angiography in diabetic macular edema.

Reza Mirshahi, Hamid Riazi-Esfahani, Elias Khalili Pour, Kaveh Fadakar, Parsa Yarmohamadi, Sayyed Amirpooya Alemzadeh, Samira Chaibakhsh, Khalil Ghasemi Falavarjani

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Reza MirshahiEye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Hamid Riazi-EsfahaniEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Elias Khalili PourEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Kaveh FadakarEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Parsa YarmohamadiYoung Researchers and Elite club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Sayyed Amirpooya AlemzadehEye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Samira ChaibakhshEye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Khalil Ghasemi FalavarjaniEye Research Center, The Five Senses Health Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. drghasemi@yahoo.com.
Iran University of Medical Sciences · IRTehran University of Medical Sciences · IRIslamic Azad University Medical Branch of Tehran · IRRasool Akram Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of current study was to evaluate different optical coherence tomography angiography (OCTA) metrics in eyes with diabetic retinopathy with and without diabetic macular edema (DME). In this retrospective study, macular OCTA images of eyes with non-proliferative or proliferative diabetic retinopathy were evaluated. Vascular density, vascular complexity and non-perfusion densities were compared between eyes with and without DME. One-hundred-thirty-eight eyes of 92 diabetic patients including 49 eyes with DME were included. In multivariate analysis, the presence of DME was positively associated with geometric perfusion deficit (GPD) in superficial capillary plexus (SCP), capillary non-perfusion (CNP) of SCP, and GPD in deep capillary plexus (DCP) (all P < 0.05). In eyes with DME, central foveal thickness was associated with VD ratio (SCP/DCP) (P = 0.001) and FAZ area (P = 0.001). In conclusion, in eyes with diabetic retinopathy, the presence of DME was associated with more extensive capillary non-perfusion compared to those with no macular edema.

Indexed as

AgedComorbidityDiabetic RetinopathyFemaleFluorescein AngiographyHumansMacular EdemaMaleMicrovascular DensityMiddle AgedMultivariate AnalysisRetrospective StudiesTomography, Optical Coherence

Identifiers

PMID34862410
PMCPMC8642537
OpenAlexW3215295831

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.