ArticleDrug and alcohol dependence2022
Alcohol use in emerging adults associated with lower rich-club connectivity and greater connectome network disorganization.
Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- White matter neural substrates in alcohol dependence with genetic risk and their role in pathological reward process.Scientific reports · 2025Article
- Association of over the counter "hangover remedy" use with alcohol use problems and consumption patterns among young adults.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
- Rich-club connectivity and structural connectome organization in youth at clinical high-risk for psychosis and individuals with early illness schizophrenia.Schizophrenia research · 2023Article
- Alcohol use in emerging adults associated with lower rich-club connectivity and greater connectome network disorganization.Drug and alcohol dependence · 2022Article
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Authors and funding
10 authors.
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Abstract
backgroundEmerging adulthood is a critical neurodevelopmental stage, with alcohol use during this period consistently associated with brain abnormalities and damage in anatomical structure and white matter integrity. However, it is less clear how alcohol use is associated with the brain's structural organization (i.e., white matter connections between anatomical regions). Recent connectome research has focused on rich-club regions, a collection of highly-interconnected hubs that are critical in brain communication and global network organization and disproportionately vulnerable to insults.
methodsFor the first time, we examined alcohol use associations with structural rich-club and connectome organization in emerging adults (N = 66).
resultsGreater lifetime drinks and current monthly drinks were significantly associated with lower rich-club organization (r
conclusionsResults provide novel evidence that alcohol use is associated with decreased rich-club connectivity and structural network disorganization. Given that both are critical in global brain communication, these results highlight the importance of examining alcohol use and brain relationships in emerging adulthood.
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