Evidence map›Paper›PMID 34861150›Full record

ArticleNeuron2022

A glial ClC Cl

Jesus Fernandez-Abascal, Christina K Johnson, Bianca Graziano, Lei Wang, Nicole Encalada, Laura Bianchi

Open access · greenAbstract read
In one paragraph

Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Glial overexpression of carbonic anhydrasemicroPublication biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Dendrite glia interactions: lessons from theFrontiers in cell and developmental biology · 2025
    Review
  14. Glia Development and Function in the NematodeCold Spring Harbor perspectives in biology · 2024
    Review
  15. Article
  16. A neurotransmitter atlas ofbioRxiv : the preprint server for biology · 2024
    Article
  17. Glial KCNQ KNeuron · 2024
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jesus Fernandez-AbascalDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Christina K JohnsonDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Bianca GrazianoDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Lei WangDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Nicole EncaladaDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Laura BianchiDepartment of Physiology and Biophysics, Miller School of Medicine, University of Miami, Miami, FL 33136, USA. Electronic address: lbianchi@med.miami.edu.
University of Miami · US

Funding

Glial ion channels in glia/neurons interactions.R01NS105616 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Laura Bianchi · 2018 to 2026
$3.2M
Glia in Touch SensationR01NS070969 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BIANCHI, LAURA · 2011 to 2015
$1.6M
NINDS NIH HHS R01 NS070969NINDS NIH HHS R01 NS105616
6 · The paper itself

Abstract

In touch receptors, glia and accessory cells play a key role in mechanosensation. However, the mechanisms underlying such regulation are poorly understood. We show, for the first time, that the chloride channel CLH-1 is needed in glia of C. elegans nose touch receptors for touch responses and for regulation of excitability. Using in vivo Ca

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsChloride ChannelsNeurogliaRatsSensory Receptor CellsTouchCaenorhabditis elegans ProteinsChloride Channelsclh-1 protein, C eleganscAMPC. elegansClC channelsGABAgliaintracellular Ca2+nociceptiontouch

Identifiers

PMID34861150
PMCPMC8813913
OpenAlexW3215507880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.