SynthesisAmerican journal of respiratory and critical care medicine2022
High-Flow Nasal Oxygen for Severe Hypoxemia: Oxygenation Response and Outcome in Patients with COVID-19.
Open access · hybridAbstract readComparative StudyMeta-Analysis
In one paragraph
Synthesis in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Comparison between high-flow nasal cannula and noninvasive ventilation in COVID-19 patients: a systematic review and meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Respective Effects of Helmet Pressure Support, Continuous Positive Airway Pressure, and Nasal High-Flow in Hypoxemic Respiratory Failure: A Randomized Crossover Clinical Trial.American journal of respiratory and critical care medicine · 2023Trial
- The Acute Respiratory Distress Syndrome (ARDS): epidemiology, etiology, molecular mechanisms, diagnosis and therapeutic strategies.Molecular biomedicine · 2026Review
- High-flow nasal therapy vs conventional oxygen therapy in mild COVID-19 hypoxaemia: a Bayesian reanalysis of the COVID-HIGH Trial.Journal of anesthesia, analgesia and critical care · 2026Article
- High-flow nasal cannula in the real world: powerful support, hidden severity.Critical care science · 2026Article
- Acute Respiratory Distress Syndrome Definitions in Adults and Children: A Comparative Narrative Review.Journal of clinical medicine · 2025Review
- Validation of Global Definition of Acute Respiratory Distress Syndrome in COVID-19 Patients: A Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Digital twins suggest a mechanistic basis for differing responses to increased flow rates during high-flow nasal cannula therapy.Intensive care medicine experimental · 2025Article
- Limitations of SpOCritical care (London, England) · 2025Observational
- Operationalizing the New Global Definition of ARDS: A Retrospective Cohort Study From South Africa.CHEST critical care · 2024Article
- Clinical review of non-invasive ventilation.The European respiratory journal · 2024Review
- Noninvasive respiratory support in the emergency department: Controversies and state-of-the-art recommendations.Journal of the American College of Emergency Physicians open · 2024Review
- Asymmetrical high-flow nasal cannula performs similarly to standard interface in patients with acute hypoxemic post-extubation respiratory failure: a pilot study.BMC pulmonary medicine · 2024Article
- From Berlin to Global: The Need for Syndromic Definitions of Acute Respiratory Distress Syndrome.American journal of respiratory and critical care medicine · 2024Article
- A New Global Definition of Acute Respiratory Distress Syndrome.American journal of respiratory and critical care medicine · 2024Article
- The Global Definition of Acute Respiratory Distress Syndrome: Ready for Prime Time?American journal of respiratory and critical care medicine · 2024Article
- The respiratory oxygenation index for identifying the risk of orotracheal intubation in COVID-19 patients receiving high-flow nasal cannula oxygen.Critical care science · 2024Observational
- Personalized Noninvasive Respiratory Support in the Perioperative Setting: State of the Art and Future Perspectives.Journal of personalized medicine · 2023Review
- Ventilatory Management of Patients with Acute Respiratory Distress Syndrome Due to SARS-CoV-2.Journal of clinical medicine · 2023Review
- Subphenotypes in patients with acute respiratory distress syndrome treated with high-flow oxygen.Critical care (London, England) · 2023Observational
Corrections and comments
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Authors and funding
19 authors at 9 institutions in 4 countries.
V Marco RanieriDepartment of Medical and Surgical Sciences.
Tommaso TonettiDepartment of Medical and Surgical Sciences.ORCID 0000-0001-9676-3595
Paolo NavalesiDepartment of Medicine, University of Padova , Padua, Italy.
Stefano NavaDepartment of Experimental, Diagnostic and Specialty Medicine , and.
Massimo AntonelliDepartment of Anesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Antonio PesentiDepartment of Pathophysiology and Transplantation University of Milan , Milan, Italy.
Giacomo GrasselliDepartment of Pathophysiology and Transplantation University of Milan , Milan, Italy.ORCID 0000-0002-1735-1400
Domenico Luca GriecoDepartment of Anesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0002-4557-6308
Luca Salvatore MengaAnesthesia and Intensive Care, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Lara PisaniDepartment of Experimental, Diagnostic and Specialty Medicine , and.
Annalisa BoscoloInstitute of Anesthesia and Intensive Care, Padova University Hospital, Padua, Italy.
Nicolò SellaDepartment of Medicine, University of Padova , Padua, Italy.
Laura PasinInstitute of Anesthesia and Intensive Care, Padova University Hospital, Padua, Italy.
Chiara MegaDepartment of Medical and Surgical Sciences.
Giacinto PizzilliAnesthesia and Intensive Care Medicine and.
Alessio Dell'OlioDepartment of Medical and Surgical Sciences.
Roberto DongilliDivision of Respiratory Diseases with Intermediate Respiratory Intensive Care Units, Central Hospital of Bolzano, Bolzano, Italy; and.
Paola RucciStatistics and Epidemiology, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum-University of Bologna , Bologna, Italy.
Arthur S SlutskyKeenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, Canada.ORCID 0000-0002-6063-3876
Intensive Care Foundation · AUUniversity of Padua · ITSpecialty Materials (United States) · USUniversità Cattolica del Sacro Cuore · ITUniversity of Milan · ITAgostino Gemelli University Polyclinic · ITOspedale di Bolzano · ITSt. Michael's Hospital · CAUniversity of Bologna · IT
Funding
CIHR 137772CIHR OV3-170344Italian Ministry of Health, Ministero della Salute project PB-0154 PROGETTO COVID-2020-12371675Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017, project J4BE7A
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19HypoxiaOxygen Inhalation TherapyRespiratory Distress SyndromeAgedFemaleHumansItalyMaleMiddle AgedPatient AcuityRespiration, ArtificialTreatment OutcomeARDSCOVID-19HFNOmechanical ventilationnoninvasive ventilation
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.