Evidence map›Paper›PMID 34861063›Full record

ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2022

Structured presurgery prehabilitation for aged patients undergoing elective surgery significantly improves surgical outcomes and reduces cost: A nonrandomized sequential comparative prospective cohort study.

Frederick H Koh, Caroline H Loh, Winson J Tan, Leonard M L Ho, Dulcena Yen, Jason M W Chua, Shawn S X Kok, Sharmini S Sivarajah, Min-Hoe Chew, Fung-Joon Foo

Open access · hybridAbstract read
In one paragraph

Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  6. Delivering prehabilitation in cancer surgery: a service evaluation at Nottingham University Hospitals.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  9. Multimodal prehabilitation in digestive oncology: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Frederick H KohColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-3717-4480
Caroline H LohDepartment of General Surgery, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.
Winson J TanColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Leonard M L HoColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Dulcena YenColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Jason M W ChuaInstitute of Molecular and Cell Biology, Agency for Science Technology and Research, Singapore, Singapore.
Shawn S X KokDepartment of Radiology, Sengkang General Hospital, Singapore, Singapore.
Sharmini S SivarajahColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Min-Hoe ChewColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Fung-Joon FooColorectal Service, Department of Surgery, Sengkang General Hospital, Singapore, Singapore.
Sengkang General Hospital · SGAgency for Science, Technology and Research · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith increasing global life expectancy, the number of major surgeries performed on aged adults invariably increases. This study aimed to examine the effectiveness of a structured prehabilitative program for aged colorectal cancer patients in improving short-term surgical outcomes.

methodsA prospective philanthropically sponsored Programme for Enhanced Elderly Recovery at Sengkang General Hospital (PEERS) was initiated in February 2017 for patients ≥70-years-old who were due to undergo elective colectomies. These patients were put through a 2- to 4-week-long program before surgery, which included geriatric assessment, nutrition supplementation, and resistance training. They were compared with patients from a similar age group before PEERS was introduced (non-PEERS).

resultsFifty-eight patients, with a median age of 78.5 (70-93) years, were recruited from a single institution to undergo PEERS. Baseline characteristics between the groups were similar. There was no significant improvement of anthropometric and functional characteristics before and after PEERS. Duration of hospitalization was shorter in the PEERS group (9 vs 11 days, P = 0.01). Both groups had similar 30-days' morbidity rates (8.6% vs 17.4%, P = 0.26). The PEERS group had significant improvement in their median EuroQol-5 Dimension score (0.70 presurgery to 0.80 6-months' postsurgery, P = 0.01). After multivariate analysis, the average duration of hospitalization in the PEERS group was 6.8 days shorter (P = 0.018; CI, 1.2-12.4) after adjusting for modality of surgery and complications. This represented a cost saving of USD$11,838.80.

conclusionA standardized prehabilitation program for aged adults reduced the duration of hospitalization, improved the quality of life after surgery, and reduced costs.

Indexed as

Preoperative ExerciseQuality of LifeAdultAgedAged, 80 and overHumansMiddle AgedPostoperative ComplicationsPreoperative CareProspective StudiesTreatment Outcomeagingcolorectal cancercostsprehabilitationsurgerysurgical outcomes

Identifiers

PMID34861063
PMCPMC9299996
OpenAlexW3215587310

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.