Evidence map›Paper›PMID 34860348›Full record

ArticleMolecular and cellular biochemistry2022

The levels of pro- and anti-inflammatory cytokines in premature infants with perinatal infections.

Akmaral K Zhumalina, Balash T Tusupkaliev, Mairamkul B Zharlykasinova, Botagoz A Zhekeyeva, Klara B Darzhanova

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Akmaral K ZhumalinaDepartment of Childhood Diseases No. 1 with Neonatology, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev Str., 030000, Aktobe, Republic of Kazakhstan. zumalina@mail.ru.ORCID http://orcid.org/0000-0002-4402-0770
Balash T TusupkalievDepartment of Childhood Diseases No. 1 with Neonatology, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev Str., 030000, Aktobe, Republic of Kazakhstan.
Mairamkul B ZharlykasinovaDepartment of Childhood Diseases No. 1 with Neonatology, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev Str., 030000, Aktobe, Republic of Kazakhstan.
Botagoz A ZhekeyevaDepartment of Childhood Diseases No. 1 with Neonatology, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev Str., 030000, Aktobe, Republic of Kazakhstan.
Klara B DarzhanovaDepartment of Normal and Topographic Anatomy with Operative Surgery, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev Str., 030000, Aktobe, Republic of Kazakhstan.
West Kazakhstan Marat Ospanov State Medical University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine infections are an urgent problem of modern neonatology. One of the causes of intrauterine infective foetal lesions is physiological immunosuppression. The purpose of this study is to investigate the cytokine status in newborns infected with perinatal infections, depending on their body weight. The study examined 145 newborns. Taking into account their body weight, they were divided into 2 groups: main and secondary. The study was conducted in the immunological laboratory of the Medical Centre of Marat Ospanov West Kazakhstan Medical University in the city of Aktobe, with the determination of the level of IgM and IgG to the herpes simplex virus (HSV) types 1, 2, cytomegalovirus (CMV), and chlamydia using the MULTISKANASCENT analyser with the "Chemo" T system. The main results of this study are the predominance of the anti-inflammatory component in both normal weight and underweight infants, which is evidence of the Th-cell-mediated immune response prevalence. The applied value of this study lies in the possibility of applying its results in practice to obtain effective methods to counteract the occurrence and development of intrauterine infections.

Indexed as

Chlamydia InfectionsCytokinesFemaleHumansInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureInflammationMaleVirus DiseasesCytokinesDiseaseIntrauterine infectionMicroflora disruptionNewborns

Identifiers

PMID34860348
OpenAlexW3216625769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.