Evidence map›Paper›PMID 34860306›Full record

ArticleBehavior genetics2022

Associations Between Traumatic Stress, Brain Volumes and Post-traumatic Stress Disorder Symptoms in Children: Data from the ABCD Study.

Daniel Bustamante, Ananda B Amstadter, Joshua N Pritikin, Timothy R Brick, Michael C Neale

Open access · hybridAbstract read
In one paragraph

Article in Behavior genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Longitudinal Sex-at-Birth and Age Analyses of Cortical Structure in the ABCD Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel BustamanteVirginia Institute for Psychiatric and Behavioral Genetics, 800 E Leigh Street, Biotech One, Box 980126, Richmond, VA, 23298, USA. bustamanted@vcu.edu.ORCID 0000-0003-0170-2242
Ananda B AmstadterVirginia Institute for Psychiatric and Behavioral Genetics, 800 E Leigh Street, Biotech One, Box 980126, Richmond, VA, 23298, USA.
Joshua N PritikinVirginia Institute for Psychiatric and Behavioral Genetics, 800 E Leigh Street, Biotech One, Box 980126, Richmond, VA, 23298, USA.
Timothy R BrickDepartment of Human Development and Family Studies, and Institute for Computational and Data Sciences, The Pennsylvania State University, University Park, PA, USA.
Michael C NealeVirginia Institute for Psychiatric and Behavioral Genetics, 800 E Leigh Street, Biotech One, Box 980126, Richmond, VA, 23298, USA.
Virginia Commonwealth University · USPennsylvania State University · US

Funding

Examining Brain Development, Context, and Culture as Mediators and Moderators of the Relation between Adverse Childhood Experiences (ACEs) and Substance (Ab)useU01DA051037 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI James M Bjork, MICHAEL CHURTON NEALE · 2020 to 2026
$11.0M
Research Training: Psychiatric &Statistical GeneticsT32MH020030 · NIMH · VIRGINIA COMMONWEALTH UNIVERSITY · PI HERMINE H MAES, MICHAEL CHURTON NEALE · 1999 to 2026
$6.7M
Extensions of Mendelian Randomization Methodology for Combined Genomic and Methylomic AnalysisR01DA049867 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI NEALE, MICHAEL CHURTON · 2020 to 2024
$1.9M
Stress-induced drinking in Returning Soldiers: Genetic and Epigenetic MechanismsK02AA023239 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI AMSTADTER, ANANDA B · 2014 to 2018
$643k
NIAAA NIH HHS K02 AA023239NIDA NIH HHS R01 DA049867NIDA NIH HHS U01 DA051037NIMH NIH HHS T32 MH020030
6 · The paper itself

Abstract

Reduced volumes in brain regions of interest (ROIs), primarily from adult samples, are associated with posttraumatic stress disorder (PTSD). We extended this work to children using data from the Adolescent Brain Cognitive Development (ABCD) Study® (N = 11,848; M

Indexed as

Stress Disorders, Post-TraumaticAdolescentBrainHumansMagnetic Resonance ImagingBrainChildrenEnvironmentGeneticMRIPTSDRegularization

Identifiers

PMID34860306
PMCPMC8860798
OpenAlexW3215108961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.