Evidence map›Paper›PMID 34860274›Full record

ReviewWorld journal of urology2022

The utility of prostate MRI within active surveillance: description of the evidence.

Georgina Dominique, Wayne G Brisbane, Robert E Reiter

Abstract readReview
In one paragraph

Review in World journal of urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Georgina DominiqueCharles R. Drew University/David Geffen School of Medicine at UCLA Medical Education Program, Los Angeles, CA, USA.
Wayne G BrisbaneInstitute of Urologic Oncology, Department of Urology, UCLA Medical Center, University of California Los Angeles, Los Angeles, CA, USA.
Robert E ReiterInstitute of Urologic Oncology, Department of Urology, UCLA Medical Center, University of California Los Angeles, Los Angeles, CA, USA. rreiter@mednet.ucla.edu.ORCID http://orcid.org/0000-0002-7962-3985

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe present an overview of the literature regarding the use of MRI in active surveillance of prostate cancer.

methodsBoth MEDLINE

resultsWithin active surveillance, baseline MRI is effective for identifying clinically significant prostate cancer and thus associated with fewer reclassification events. A positive initial MRI (≥ PI-RADS 3) with GG1 identified at biopsy has a positive predictive value (PPV) of 35-40% for reclassification by 3 years. MRI possessed a stronger negative predictive value, with a negative MRI (≤ PI-RADS 2) yielding a negative predictive value of up to 85% at 3 years. Surveillance MRI, obtained after initial biopsy, yielded a PPV of 11-65% and NPV of 85-95% for reclassification.

conclusionMRI is useful for initial risk stratification of prostate cancer in men on active surveillance, especially if MRI is negative when imaging is obtained during surveillance. While useful, MRI cannot replace biopsy and further research is necessary to fully integrate MRI into active surveillance.

Indexed as

Magnetic Resonance ImagingWatchful WaitingHumansMalePredictive Value of TestsProstatic NeoplasmsActive surveillanceMRIPI-RADSProstate cancer

Identifiers

PMID34860274
PMCPMC8813688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.