Evidence map›Paper›PMID 34859939›Full record

SynthesisJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2022

Does immediate dentin sealing influence postoperative sensitivity in teeth restored with indirect restorations? A systematic review and meta-analysis.

Uros Josic, Maicon Sebold, Rodrigo B E Lins, Jelena Savovic, Claudia Mazzitelli, Tatjana Maravic, Annalisa Mazzoni, Lorenzo Breschi

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Interdisciplinary Delphi study by PROSEC North America: Recommendations on single indirect restorations made from ceramic and nonmetallic biomaterials for posterior teeth.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Pooled it
  2. Pooled it
  3. Does immediate dentin sealing influence postoperative sensitivity in teeth restored with indirect restorations? A systematic review and meta-analysis.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2022
    Pooled it
  4. Does Tooth Position Change Between Preparation and Cementation in Overlay Restoration? A Clinical Evaluation With/Out Interappointment Provisionalization.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 6 countries.

Uros JosicDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.
Maicon SeboldDepartment of Restorative Dentistry, Operative Dentistry Devision, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Rodrigo B E LinsDepartment of Restorative Dentistry, Operative Dentistry Devision, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.ORCID https://orcid.org/0000-0002-8224-6578
Jelena SavovicPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Claudia MazzitelliDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.
Tatjana MaravicDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.
Annalisa MazzoniDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.
Lorenzo BreschiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna.ORCID https://orcid.org/0000-0001-7621-226X
GNA University · INUniversidade Estadual da Paraíba · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Belgrade · RSUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study comprehensively reviewed clinical trials that investigated the effect of immediate dentin sealing (IDS) technique on postoperative sensitivity (POS) and clinical performance of indirect restorations. MATERIALS AND

methodsThe systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses statement, and was guided by the PICOS strategy. Clinical trials in which adult patients received at least one indirect restoration cemented with IDS approach and one restoration cemented following the delayed dentin sealing (DDS) were considered.

resultsFollowing title screening and full-text reading, four studies met the inclusion criteria and were included for qualitative synthesis, while two studies were selected for quantitative synthesis. According to Risk of bias-2 tool, two studies were classified as "some concerns" for the outcome POS. No statistically significant differences were found between teeth restored with indirect restorations using the IDS and DDS approach for POS (p > 0.05), neither at the baseline (very low certainty of evidence according to GRADE) nor after 2 years of follow-up (low certainty of evidence according to GRADE).

conclusionThere is low-certainty evidence that IDS does not reduce POS in teeth restored with indirect restorations. CLINICAL SIGNIFICANCE: There is no clinical evidence to favor IDS over DDS when restoring teeth with indirect restorations.

Indexed as

DentinMolarAdultComposite ResinsHumansComposite Resinsimmediate dentin sealingindirect restorationsystematic review

Identifiers

PMID34859939
PMCPMC9300029
OpenAlexW3216857957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.