ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2021
Role and mechanism of necrostin-1 in promoting oxidative stress response of macrophages in high glucose condition.
Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Hyperglycemic microenvironment-driven periodontal tissue defects: pathogenic mechanisms and therapeutic advances.Frontiers in dental medicine · 2026Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesTo investigate the role and molecular mechanism of necrostatin-1 (Nec-1), a specific programmed cell necrosis inhibitor, in promoting the oxidative stress response of macrophages under high glucose (HG) environment.
methodsMacrophages were cultured in control (5.5 mmol·L
resultsThe HG group had increased ROS level and MDA activity (
conclusionsHG promotes oxidative stress on macrophages by upregulating RIP1 expression.
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Registered trials
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