ArticleInternational journal for numerical methods in biomedical engineering2022
Association of vortical structures and hemodynamic parameters for regional thrombus accumulation in abdominal aortic aneurysms.
Article in International journal for numerical methods in biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- A rare case of non-obstructed total anomalous pulmonary venous connection with a giant superior vena cava aneurysm complicated by acute young ischemic stroke.BMC cardiovascular disorders · 2026Article
- Physics-Based Growth and Remodeling Modeling for Virtual Abdominal Aortic Aneurysm Evolution and Growth Prediction.medRxiv : the preprint server for health sciences · 2026Article
- Integrated Assessment of Wall Shear Stress-Related Hemodynamic Parameters in Abdominal Aortic Aneurysms: A Retrospective Cross-Sectional Study on Ruptured Cases.International journal for numerical methods in biomedical engineering · 2026Article
- Association of intraluminal thrombus in thoracoabdominal aortic aneurysms with a blood stasis model.Frontiers in cardiovascular medicine · 2026Article
- Modeling Techniques and Boundary Conditions in Abdominal Aortic Aneurysm Analysis: Latest Developments in Simulation and Integration of Machine Learning and Data-Driven Approaches.Bioengineering (Basel, Switzerland) · 2025Review
- A hemodynamic analysis of energy loss in abdominal aortic aneurysm using three-dimension idealized model.Frontiers in physiology · 2024Article
- CT-based comparison of porcine, ovine, and human pulmonary arterial morphometry.Scientific reports · 2023Article
- Effect of Intraluminal Thrombus Burden on the Risk of Abdominal Aortic Aneurysm Rupture.Journal of cardiovascular development and disease · 2023Article
- Intraluminal Thrombus Characteristics in AAA Patients: Non-Invasive Diagnosis Using CFD.Bioengineering (Basel, Switzerland) · 2023Article
- Effects of cardiac function alterations on the risk of postoperative thrombotic complications in patients receiving endovascular aortic repair.Frontiers in physiology · 2022Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
The intraluminal thrombus (ILT) has been shown to negatively impact the progression of the abdominal aortic aneurysms (AAAs). The formation of this thrombus layer has been connected to the local flow environment within AAAs, but the specific mechanisms leading to thrombus formation are still not fully understood. Our study investigated the association between vortical structures, near-wall hemodynamic metrics (e.g., time averaged wall shear stress (TAWSS) and oscillatory shear index (OSI)), and ILT accumulation in a longitudinal cohort of 14 AAAs (53 scans total). Vortices and hemodynamic parameters were estimated using hemodynamic simulations performed to each scan of each patient and compared to local 3D changes of ILT thickness between two consecutive scans (ΔILT). Results showed that vortices formed and remained strong and close to the lumen surface in AAAs without an ILT, while in AAAs with ILTs these detached from the lumen surface and dissipated nearby wall region where an increase in ILT thickness was observed. Although low TAWSS was observed in regions with and without ILT accumulation, an inverse correlation between
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