Evidence map›Paper›PMID 34859526›Full record

Trial reportAddiction (Abingdon, England)2022

The old and familiar meets the new and unknown: patient and clinician perceptions on e-cigarettes for smoking reduction in UK general practice, a qualitative interview study.

Charlotte Albury, Rebecca Barnes, Anne Ferrey, Tim Coleman, Hazel Gilbert, Felix Naughton, Paul Aveyard, Rachna Begh, MaSC Study Investigators

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 5 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  4. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2024
    Pooled it
  5. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Trial
  7. Article
  8. How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  9. Article
  10. Vaping Trends and Outcomes in Primary Total Joint Arthroplasty Patients: An Analysis of 21,341 Patients.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Charlotte AlburyNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-1036-6626
Rebecca BarnesNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Anne FerreyNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Tim ColemanDivision of Primary Care, University of Nottingham, Nottingham, UK.ORCID 0000-0002-7303-4805
Hazel GilbertDept. of Primary Care and Population Health, University College London, London, UK.
Felix NaughtonSchool of Health Sciences, University of East Anglia, Norwich, UK.ORCID 0000-0001-9790-2796
Paul AveyardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-1802-4217
Rachna BeghNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
MaSC Study Investigators
University of Oxford · GBDepartment of Health and Social Care · GBUniversity of East Anglia · GBUniversity of Nottingham · GB

Funding

Cancer Research UK 23875
6 · The paper itself

Abstract

BACKGROUND AND

aimsClinicians could promote e-cigarettes for harm reduction to people who smoke but cannot stop, but many clinicians feel uneasy doing so. In a randomized controlled trial (RCT), primary care clinicians offered free e-cigarettes and encouraged people with chronic diseases who were unwilling to stop smoking to switch to vaping. We interviewed clinicians and patients to understand how to adopt harm reduction in routine practice.

designQualitative analysis nested within an RCT, comprising thematic analysis of semi-structured interviews with primary care clinicians who delivered the trial intervention, and patients who took part.

settingPrimary care clinics in England. PARTICIPANTS/CASES: Twenty-one patients and 11 clinicians, purposively sampled from an RCT. MEASUREMENTS: We qualitatively explored patients' and clinicians' experiences of: being offered/offering an e-cigarette, past and current perceptions about e-cigarettes and applying a harm reduction approach.

findingsFour themes captured clinicians' and patients' reported perspectives. These were: (1) concepts of safety/risk, with clinicians concerned about recommending a product with unknown long-term risks and patients preferring the known risks of cigarettes; (2) clinicians felt they were going out on a limb by offering these as though they were prescribing them, whereas patients did not share this view; (3) equating quitting with success, as both patients and clinicians conceptualized e-cigarettes as quitting aids; and (4) unchanged views, as clinicians reported that training did not change their existing views about e-cigarettes. These themes were united by the higher-order concept: 'The old and familiar meets the new and unknown', as a contradiction between this new approach and long-established methods underpinned these concerns.

conclusionsA qualitative analysis found barriers obstructing clinicians and patients from easily accepting e-cigarettes for harm reduction, rather than as aids to support smoking cessation: clinicians had difficulty reconciling harm reduction with their existing ethical models of practice, even following targeted training, and patients saw e-cigarettes as quitting aids.

Indexed as

Electronic Nicotine Delivery SystemsGeneral PracticeSmoking ReductionVapingEnglandHumansQualitative Researche-cigarettesfamily practiceharm reductionPrimary carequalitative interviewssmoking reduction

Identifiers

PMID34859526
PMCPMC9306504
OpenAlexW3217077119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.