Evidence map›Paper›PMID 34858976›Full record

ArticleFrontiers in cell and developmental biology2021

Malaria Parasites Hijack Host Receptors From Exosomes to Capture Lipoproteins.

Naoyuki Iso-O, Keisuke Komatsuya, Fuyuki Tokumasu, Noriko Isoo, Tomohiro Ishigaki, Hiroshi Yasui, Hiroshi Yotsuyanagi, Masumi Hara, Kiyoshi Kita

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Reduced Cholesterol Levels during Acute Human Babesiosis.Pathogens (Basel, Switzerland) · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Naoyuki Iso-OThe Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Keisuke KomatsuyaDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Fuyuki TokumasuDepartment of Lipidomics, The University of Tokyo, Tokyo, Japan.
Noriko IsooDepartment of Physiology, Teikyo University School of Medicine, Tokyo, Japan.
Tomohiro IshigakiThe Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Hiroshi YasuiThe Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Hiroshi YotsuyanagiThe Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Masumi HaraDepartment of 4th Internal Medicine, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Kiyoshi KitaDepartment of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPNagasaki University · JPTokyo Metropolitan Institute of Medical Science · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria parasites cannot multiply in host erythrocytes without cholesterol because they lack complete sterol biosynthesis systems. This suggests parasitized red blood cells (pRBCs) need to capture host sterols, but its mechanism remains unknown. Here we identified a novel high-density lipoprotein (HDL)-delivery pathway operating in blood-stage

Indexed as

cholesterolexosomeslipidlipoproteinsmalariaplasmodium falciparumscavenger receptors

Identifiers

PMID34858976
PMCPMC8631964
OpenAlexW3213503966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.