Evidence map›Paper›PMID 34858973›Full record

ReviewFrontiers in cell and developmental biology2021

Ferroptosis: New Dawn for Overcoming the Cardio-Cerebrovascular Diseases.

Meng-Yi Luo, Jian-Hui Su, Shao-Xin Gong, Na Liang, Wen-Qian Huang, Wei Chen, Ai-Ping Wang, Ying Tian

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. The role of ferroptosis in vascular endothelial cells and its role in the pathogenesis of cervical spondylosis of vertebral artery type: a comprehensive review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Suppression of lncRNABioengineered · 2022
    Article
  9. Article
  10. Frontiers in neurology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Meng-Yi LuoInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Jian-Hui SuInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Shao-Xin GongDepartment of Pathology, First Affiliated Hospital, University of South China, Hengyang, China.
Na LiangDepartment of Anesthesiology, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Wen-Qian HuangInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Wei ChenInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Ai-Ping WangInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
Ying TianInstitute of Clinical Research, Affiliated Nanhua Hospital, University of South China, Hengyang, China.
University of South China · CNFirst Affiliated Hospital of University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic balance of cardiomyocytes and neurons is essential to maintain the normal physiological functions of heart and brain. If excessive cells die in tissues, serious Cardio-Cerebrovascular Diseases would occur, namely, hypertension, myocardial infarction, and ischemic stroke. The regulation of cell death plays a role in promoting or alleviating Cardio-Cerebrovascular Diseases. Ferroptosis is an iron-dependent new type of cell death that has been proved to occur in a variety of diseases. In our review, we focus on the critical role of ferroptosis and its regulatory mechanisms involved in Cardio-Cerebrovascular Diseases, and discuss the important function of ferroptosis-related inhibitors in order to propose potential implications for the prevention and treatment of Cardio-Cerebrovascular Diseases.

Indexed as

cardio-cerebrovascular diseaseferroptosisinflammationironlipid peroxidation

Identifiers

PMID34858973
PMCPMC8632439
OpenAlexW3214188616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.