Evidence map›Paper›PMID 34858905›Full record

ReviewFrontiers in pediatrics2021

Barriers and Proposed Solutions to a Successful Implementation of Pediatric Sepsis Protocols.

Daniela Nasu Monteiro Medeiros, Audrey Ogawa Shibata, Cristiane Freitas Pizarro, Maria de Lourdes Alves Rosa, Marta Pessoa Cardoso, Eduardo Juan Troster

Abstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Be-SNAP: the Belgian Sepsis National Action Plan.Frontiers in public health · 2025
    Article
  4. Article
  5. Early Antibiotics in Septic Shock: A Desirable Goal but "Curb Your Enthusiasm".Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniela Nasu Monteiro MedeirosPediatric Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Audrey Ogawa ShibataPediatric Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Cristiane Freitas PizarroPediatric Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Maria de Lourdes Alves RosaHealth Practices Department, Hospital Municipal Dr Moysés Deutsch - M'Boi Mirim, São Paulo, Brazil.
Marta Pessoa CardosoPediatric Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Eduardo Juan TrosterFaculdade Israelita de Ciências em Saúde, Hospital Albert Einstein, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implementation of managed protocols contributes to a systematized approach to the patient and continuous evaluation of results, focusing on improving clinical practice, early diagnosis, treatment, and outcomes. Advantages to the adoption of a pediatric sepsis recognition and treatment protocol include: a reduction in time to start fluid and antibiotic administration, decreased kidney dysfunction and organ dysfunction, reduction in length of stay, and even a decrease on mortality. Barriers are: absence of a written protocol, parental knowledge, early diagnosis by healthcare professionals, venous access, availability of antimicrobials and vasoactive drugs, conditions of work, engagement of healthcare professionals. There are challenges in low-middle-income countries (LMIC). The causes of sepsis and resources differ from high-income countries. Viral agent such as dengue, malaria are common in LMIC and initial approach differ from bacterial infections. Some authors found increased or no impact in mortality or increased length of stay associated with the implementation of the SCC sepsis bundle which reinforces the importance of adapting it to most frequent diseases, disposable resources, and characteristics of healthcare professionals. Conclusions: (1) be simple; (2) be precise; (3) education; (5) improve communication; (5) work as a team; (6) share and celebrate results.

Indexed as

barrierschildrenimplementationmortalityoutcomesprotocol and guidelines

Identifiers

PMID34858905
PMCPMC8631453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.