Evidence map›Paper›PMID 34858869›Full record

ArticleFrontiers in cellular and infection microbiology2021

Caiqin Wang, Qing He, Yingxuan Yin, Yinjuan Wu, Xuerong Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Food and waterborne parasitology · 2026
    Article
  7. Article
  8. Frontiers in cellular and infection microbiology · 2026
    Article
  9. The metastasis landscape ofFrontiers in immunology · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Journal of Korean medical science · 2025
    Review
  15. Correlation analysis of the impact ofMicrobiology spectrum · 2025
    Article
  16. Frontiers in immunology · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Caiqin WangDepartment of Medical Oncology, Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qing HeDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yingxuan YinDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Yinjuan WuDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Xuerong LiDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNChina Atomic Energy Authority · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological functions of growth factor, such as granulins, have been explored in parasites, and we elucidated that

Indexed as

Clonorchis sinensisLiver NeoplasmsAnimalsCell Line, TumorCell MovementCell ProliferationErbB ReceptorsGranulinsHepatocytesHumansMAP Kinase Signaling SystemPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionEGFR protein, humanErbB ReceptorsGranulinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktClonorchis sinensis granulin (CsGRN)hepatocytemalignant transformationPI3K/Akt signaling pathwaysRAS/MAPK/ERK signaling pathways

Identifiers

PMID34858869
PMCPMC8631275
OpenAlexW3212208752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.